生物技术通报2017，Vol.33Issue(10)：80-87,8.DOI:10.13560/j.cnki.biotech.bull.1985.2017-0223
细菌群体感应淬灭酶及其病害防治研究进展
Research Progress on Microbial Quorum Quenching Enzymes and Their Control of Plant Diseases
摘要
Abstract
The phenomenon of information exchanging through signal molecules between microbial cells is the Quorum Sensing(QS). QS is widely present in microorganisms,and can modulate the expression of specific genes,especially virulence factors in pathogenic microorganisms. Quorum Quenching(QQ)is a new therapeutic strategy of plant diseases based on QS. QQ can be achieved by interfering QS from inhibiting the synthesis or detection of the signal molecules,or by enzyme-catalyzed degradation or modification of the signal molecules. Degrading signal molecules by using QQ enzymes is one of the most effective and nontoxic ways of QQ. So far,QQ enzymes of various microbial signaling molecules have been reported,especially N-acyl homoserine lactones(AHLs)and cis-11-methyl-2-dodecenoic acid were deeply investigated. In this review,we summarize and analyze the research status,deficiencies and the future development of QQ enzymes and their control of plant diseases,for laying a solid foundation for developing new,green and safe measures of disease control.关键词
群体感应/群体感应淬灭酶/酰基高丝氨酸内酯/顺-11-甲基-2-癸烯酸Key words
quorum sensing/quorum quenching enzymes/N-acyl homoserine lactones/cis-11-methyl-2-dodecenoic acid引用本文复制引用
范兴辉,王惠杉,何杰华,叶田,阳芳,陈少华..细菌群体感应淬灭酶及其病害防治研究进展[J].生物技术通报,2017,33(10):80-87,8.基金项目
国家重点基础研究发展计划(2015CB150600),广东省杰出青年科学基金(2015A030306038),广东省高校青年创新人才项目(2014KQNCX036) （2015CB150600）
