实用医学杂志2017，Vol.33Issue(18)：3040-3044,5.DOI:10.3969/j.issn.1006-5725.2017.18.015
中老年高血压患者静息心率与颈动脉粥样硬化的相关性
The correlation between resting heart rate and carotid atherosclerosis in middle-aged and elderly hyperten-tion
摘要
Abstract
Objective To expore the correlation between resting heart rate(RHR)and carotid atheroscle-rosis in middle-aged and elderly hypertention. Methods A total of 1043 middle-aged and elderly essential hyper-tention were selected and divided into 3 groups according to the RHR:< 70(Group A,n = 406),70～79(Group B,n=364),and≥80 beats/min(Group C,n=273). The patients′fasting blood-glucose(FBG),blood lipids, homocysteine (Hcy) and serum creatinine (SCr) levels were measured. Carotid artery intima-media thickness (CAIMT) and carotid artery diameter (CADIA) were measured by ultra-sonography ,and carotid artery plaques were investigated. Bi-variate correlation analysis was adopted to analyze the correlation between RHR and CAIMT , CADIA. Logistic regression analysis was employed to analyze the influential factors in carotid artery plaques. Mean-while,sub-group analysis of different ages was performed. Results The detection rates of carotid artery plaques in the Group A,B and C were 59.1％,63.7％and 69.6％respectively. Differences in detection rates of carotid artery plaques among 3 groups showed statistical significance(P<0.05). RHR(OR 1.165,95％CI 1.094～1.482,P=0.037) was a risk factor of carotid artery plaques. Significant positive correlations were found between RHR and CAIMT ,CADIA (r = 0.115 ,0.123;P = 0.005 ,0.003). Conclusions RHR was closely related with carotid artery plaques,CAIMT,and CADIA in middle-aged and elderly hypertention. RHR can be recognized as a predic-tive factor of carotid atherosclerosis in middle-aged and elderly hypertention.关键词
静息心率/颈动脉粥样硬化/中老年高血压Key words
restig heart rate/carotid atherosclerosis/middle-aged and elderly hypertention引用本文复制引用
侯文静,王晓飞,孙晓燕,周丽娟,刘敏..中老年高血压患者静息心率与颈动脉粥样硬化的相关性[J].实用医学杂志,2017,33(18):3040-3044,5.基金项目
2016年河南省科技惠民计划(编号:162207310003) （编号:162207310003）
