西北国防医学杂志2017,Vol.38Issue(9):569-573,5.DOI:10.16021/j.cnki.1007-8622.2017.09.003
高原驻训官兵不同时间点血常规及血清IL-6、IL-8水平的改变及意义
Changes and significance of routine blood and serum level of IL-6, IL-8 on officers and soldiers training in plateau at different time points
摘要
Abstract
Objective:To evaluate the changes of blood routine,IL-6,IL-8 of soilders in the plateau under low oxygen condition,and to provide the basis for the security of the plateau.Methods:Parameters of venous blood cells were examined in 300 soldiers before and after reached plateau 1,2 and 3 months by automated hematology analyzer.ELISA method was used to examine the levels of serum IL-6,IL-8 in 40 soldiers at the same time.Results:RBC、Hb in 4 200 m altitude at first month were significantly higher than those in altitude of 1000 m (P< 0.01),and increased more significantly with time.WBC also increased significantly after reached plateau 1 month(P<0.01),but decreased slightly after 2 months and still higher than that in altitude of 1000 m (P<0.01),then remained stable.PLT was fluctuated slightly after reached plateau (P <0.01).The levels of serum IL-6,IL-8 in soldiers were decreased remarkably(P < 0.01),and the longer stay time,decreased more significantly.Conclusion:High altitude hypoxia environment can affect and change the parameters of venous blood cells.With the time of stayed plateau longer,the inflammatory response can be weakened,and adaptive traning and hong capsules can significantly reduce injuries induced by hypoxia.关键词
高原/驻训官兵/血常规/IL-6/IL-8/炎性反应Key words
high altitude/soldiers stationed in plateau/blood routine/IL-6/IL-8/inflammatory response分类
医药卫生引用本文复制引用
杜亚利,路宁维,白洁,王美亮,郭馨云,王美波..高原驻训官兵不同时间点血常规及血清IL-6、IL-8水平的改变及意义[J].西北国防医学杂志,2017,38(9):569-573,5.基金项目
兰州军区医药卫生科研计划资助项目(CLZ14JB24) (CLZ14JB24)