中国全科医学2017，Vol.20Issue(25)：3122-3126,5.DOI:10.3969/j.issn.1007-9572.2017.25.012
不同危险分层肺血栓栓塞患者的影响因素、临床表现及血脂水平研究
Clinical Manifestations and Serum Lipid Levels of Patients with Pulmonary Thromboembolism in Different Risk Stratification and the Influencing Factors of Risk Stratification
摘要
Abstract
Objective To explore the clinical manifestations and serum lipid levels of patients with pulmonary thromboembolism (PTE) in different risk stratification and the influencing factors of risk stratification,in order to provide a rational treatment plan and preliminary diagnostic evidence for different risk stratified PTE.Methods A total of 60 patients with PTE were enrolled from 2010 to 2014 in Shengjing Hospital of China Medical University in this study.According to the PTE risk classification standards proposed in the Guidelines on Diagnosis and Management of Acute Pulmonary Embolism which was developed by the European Society of Cardiology (ESC) in 2014,PTE patientswere divided into high/medium risk PTE group (n =35) and low risk PTE group (n =25).The clinical data of two groups such as baseline information,clinical manifestations and serum lipid levels were collected and the baseline information was statistically analyzed through multivariate Logistic regression to explore the influencing factors of risk stratification.Results The difference of age between two groups was statistically significant (P ＜ 0.05).There were no significant differences in the proportion of male,smoking,alcohol consumption,hypertension,coronary heart disease,diabetes mellitus,cerebrovascular disease,deep venous thrombosis (DVT),recent surgery,trauma and long-term bed rest between two groups (P ＞0.05).Age is the influencing factor of PTE risk stratification [OR =1.145,95％ CI (1.059,1.238),P ＜ 0.05].There were significant differences in the incidence of palpitations,hcmoptysis or blood-stained sputum,syncope and feeling impending death between two groups (P ＜ 0.05).There were no significant differences in the incidence of dyspnea,cough,chest pain and triple syndromes between two groups (P ＞ 0.05).There were statistically significant differences in the incidence of tachycardia and jugular vein distension between two groups (P ＜0.05).There were no significant differences in the incidence of lower extremity swelling,fervescence,shortness of breath,moist rale,cyanosis,accentuation of second heart sound and wheeze between two groups (P ＞ 0.05).There were no significant differences in levels of serum total cholesterol,triglyceride,high density lipoprotein,low density lipoprotein,apolipoprotein A Ⅰ and apolipoprotein B between two groups (P ＞ 0.05).Conclusion Advanced age is the risk factor of high/medium risk of PTE.When PTE patients develop the clinical symptoms such as palpitations,syncope,feeling impending death,tachycardia,jugular vein distension and so on,the onset of high/medium risk of PTE should be forecasted.关键词
肺血栓栓塞/危险分层/影响因素分析/临床特征/血脂Key words
Pulmonary thromboembolism/Risk stratification/Root cause analysis/Clinical features/Serum lipid分类
医药卫生引用本文复制引用
赵晓宇,陈莹莹,叶茂盛,吴莎,郑锐..不同危险分层肺血栓栓塞患者的影响因素、临床表现及血脂水平研究[J].中国全科医学,2017,20(25):3122-3126,5.基金项目
2015年辽宁省临床能力建设项目(青年)(LNCCC-D14-2015) （青年）
