中国输血杂志2017,Vol.30Issue(8):901-903,3.DOI:10.13303/j.cjbt.issn.1004-549x.2017.08.014
无偿献血者HIV检测和归队情况分析
Voluntary blood donors HIV Testing and regression analysis
摘要
Abstract
Objective This study aims to analyze the results of the screening and regression tests on voluntary blood donors for HIV detection and to provide data support for screening,verification and reentry strategy for blood donors.Methods The donated blood samples were acquired from Fujian blood center,dating from April 16th,2012 to June 30th,2016.Anti-HIV ELISA and NAT tests were performed on these samples in 344 515 cases.Anti-HIV ELISA reactive and (or) HIV RNA reactive donor samples were then confirmed by HIV confirmatory laboratory.Donors confirmed by western blot (WB) as anti-HIV negative and HIV RNA non-reactive will be considered valid to rejoin after six months.Results 361 donors were HIV reactive.98 out of the 361 were confirmed anti-HIV ELISA reactive and 90 of which are determined positive in the WB test while 8 cases lost contact with the donors;1 sample was tested to be anti-HIV ELISA non-reactive but HIV RNA reactive;1 case was confirmed positive by WB;There were 262 anti-HIV ELISA reactive but HIV RNA non reactive cases,and 259 cases were confirmed negative by WB while 3 cases lost contact to the donors.In 91 anti-HIV reactive donors,the WB response band type was HIV-1.10 out of the 29 returned blood donors were allowed to rejoin,7 of which were considered eligible for blood donation.Conclusion The HIV infection type in blood donors in Fuzhou were mainly type 1;HIV RNA tests are highly specific to HIV infected samples;The combination of NAT,ELISA screening tests and reentry strategy would ensure the donors' right to donate while maintain safty requirements in blood donation.关键词
献血者/HIV/核酸检测/WB反应带型/归队Key words
blood donors/HIV/NAT(nucleic acid test)/WB reaction band type/reentry分类
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王丽梅,池泉,林授,何小兰..无偿献血者HIV检测和归队情况分析[J].中国输血杂志,2017,30(8):901-903,3.