中国实验动物学报2017，Vol.25Issue(5)：519-523,5.DOI:10.3969/j.issn.1005-4847.2017.05.009
电针对椎间盘脱出模型犬体感诱发电位的影响
Effect of electroacupuncture on somatosensory evoked potentials in dog models of intervertebral disc prolapse
摘要
Abstract
Objective To study the effect of electroacupuncture on repair of spinal cord injury and its effect on somatosensory evoked potential ( SEP) in dog models of intervertebral disc prolapse. Methods Nine Beagle dogs were randomly divided into three groups. In the model group and electroacupuncture group, the dog disc prolapse models were made by balloon compression, and in the electroacupuncture group, electroacupuncture was used every day for 14 days after operation. The model group was not treated after surgery. Sham operation was performed in the control group. Each dog was scored according to the Texas Spinal Cord Injury Scale for Dogs (TSCIS) scores before surgery (day 0) and on days 1, 4, 7, 14 after surgery. At the same time, SEP wave was measured using an EMG Evoked Potential Measuring Systerm and its latency and amplitude were analyzed. Results There was a significant difference in TSCIS scores between the model group, electroacupuncture group and control group at 1 day after operation. There was a significant difference between the electroacupuncture and model groups at 14 days after surgery. The amplitude of SEP in the model and electroacupuncture groups was significantly different from that in the control group at 1 day after operation, and there was a significant differ-ence between the electroacupuncture and model groups at 14 days after operation. There was a significant difference in the latency of SEP between the model and electroacupuncture groups at 4 days after operation, and between the electroacupunc-ture and model groups after at 14 days after operation. Conclusions Electroacupuncture can effectively promote healing of spinal cord injury in dogs with intervertebral disc prolapse, improve the TSCIS scores, restore SEP waveform, shorten the latency and enhance the amplitude. SEP can reflect the degree of spinal cord injury to a certain extent, and can be used to evaluate the effect of electroacupuncture treatment in these dogs.关键词
椎间盘脱出模型犬/电针/体感诱发电位/潜伏期/波幅/犬Key words
Intervertebral disc prolapse/Electroacupuncture/Somatosensory evoked potential/Latency/Ampli-tude/Dogs分类
生物科学引用本文复制引用
李拓,孔学礼,丛心宇,朱玉欣,姜代勋,陈武..电针对椎间盘脱出模型犬体感诱发电位的影响[J].中国实验动物学报,2017,25(5):519-523,5.基金项目
国家自然科学基金项目(No. 31372473) （No. 31372473）
北京农学院学位与研究生教育改革与发展项目(No. 5056516004/024). （No. 5056516004/024）
