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大鼠急性心肌梗死模型制备方法研究进展

曹珏 李贻奎 陈孟倩 姚魁武

中国比较医学杂志2017,Vol.27Issue(10):96-100,5.
中国比较医学杂志2017,Vol.27Issue(10):96-100,5.DOI:10.3969.j.issn.1671-7856.2017.10.019

大鼠急性心肌梗死模型制备方法研究进展

Research progress on preparation of rat models of acute myocardial infarction

曹珏 1李贻奎 2陈孟倩 3姚魁武1

作者信息

  • 1. 中国中医科学院广安门医院,北京 100053
  • 2. 北京中医药大学,北京 100029
  • 3. 中国中医科学院西苑医院,北京 100091
  • 折叠

摘要

Abstract

Acute myocardial infarction is one of the major causes of death in the world. Research on animal models of myocardial infarction has a great significance in improving the pathophysiology, diagnosis and treatment of human myocardial infarction. At present, problems such as low survival rate and complicated preparation still exist. In recent years, some progress has been made in the preparation of animal myocardial infarction models, which can improve the survival rate, qualified rate and speed. This paper analyzes the preparation of rat models of acute myocardial infarction and related research, combined with actual factors to simplify the process of preparation and improve the skills of scientific researchers, so as to provide a source of stable and reliable acute myocardial infarction models for medical research.

关键词

大鼠/急性心肌梗死模型/自主呼吸/冠脉结扎/麻醉/检测指标

Key words

Rat/Acute myocardial infarction model/Spontaneous breathing/Coronary artery ligation/Anaesthesia/Detection indicator

分类

医药卫生

引用本文复制引用

曹珏,李贻奎,陈孟倩,姚魁武..大鼠急性心肌梗死模型制备方法研究进展[J].中国比较医学杂志,2017,27(10):96-100,5.

基金项目

国家自然科学基金资助项目(81173449). (81173449)

中国比较医学杂志

OA北大核心CSTPCD

1671-7856

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