中国实用口腔科杂志2017，Vol.10Issue(9)：535-539,5.DOI:10.19538/j.kq.2017.09.006
半导体激光与他克莫司治疗糜烂型口腔扁平苔藓疗效比较研究
Comparison of diode laser and tacrolimus in the treatment of erosive-atrophic oral lichen planus
彭川洋 1姜艾佳 1李艳杰 1张英1
作者信息
- 1. 中国医科大学口腔医学院口腔急诊·黏膜病科,辽宁沈阳110002
- 折叠
摘要
Abstract
Objective To evaluate the efficacy between low-level diode laser of 810 nm and topical tacrolimus in the treatment of erosive-atrophic oral lichen planus (OLP).Methods A total of 60 erosive-atrophic OLP patients were randomly divided into experimental and control groups,with 30 cases in each group.Experimental group received 810 nm diode laser as local irradiation therapy;the control group received drug treatmemt with tacrolimus gel (0.1％).Evaluations were performed once a month during treatment and at the 3rd month and the 6th month.Results Sign score,pain score,and lesion severity were reduced in both groups.No significant differences were found between the two groups.But in the follow-up period after treatment,the recurrence rate of the experimental group was significantly lower than the control group(P ＜ 0.05).Meanwhile,nine patients of the control group reported side effects after the first one week of drug application.No side effects were found in the experimental group.Conclusion Diode laser treatment is as effective as topical tacrolimus therapy without any adverse effects in the treatment of erosive-atrophic OLP.Diode laser therapy can reduce recurrence and its post efficacy is superior to tacrolimus.Diode laser therapy can be a promising alternative therapy in the treatment of erosive-atrophic OLP.关键词
半导体激光/口腔扁平苔藓/糜烂/他克莫司Key words
diode laser/oral lichen planus/erosive-atrophic/tacrolimus分类
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彭川洋,姜艾佳,李艳杰,张英..半导体激光与他克莫司治疗糜烂型口腔扁平苔藓疗效比较研究[J].中国实用口腔科杂志,2017,10(9):535-539,5.
