中成药2017，Vol.39Issue(10)：2024-2029,6.DOI:10.3969/j.issn.1001-1528.2017.10.007
紫贝止咳颗粒治疗急性气管-支气管炎的多中心临床观察
Multi-center clinical observation of Zibei Zhike Granules on acute broncho-bronchitis
摘要
Abstract
AIM To observe the clinical effects and safety of Zibei Zhike Granules (Asteris Radix et Rhizoma,Ardisiae japonicae Herba,Fritiliariae cirrhosae Bulbus,etc.) for acute broncho-bronchitis with remained toxicity lingering lung.METHODS A multi-center,randomized,double-blinded,double-simulation and positive drug parallel controlled trial was adopted.Two hundred and forty cases of patients with the 1 ∶ 1 ratio were assigned to treatment and control group.The treatment group were treated with Zibei Zhike Granules and the control group were treated with Zikebao Tablets (Asteris Radix et Rhizoma,Citri rubrum exocarpium,Platycodi Radix,etc.).The treatment course lasted five days.RESULTS The total effective rate of acute broncho-bronchitis in the treatment group was 73.04％,and 54.78％ in the control group.There was statistical significance between the total effective rate of the two groups (P ＜ 0.01).The total effective rate of traditional Chinese medicine syndrome in the treatment group was 73.91％ and 60.86％ in the control group,and there was statistical significance between the total effective rate of the two groups (P ＜ 0.05).The treatment group showed better clinical effects in improving individual symptoms of cough and spitting sputum.CONCLUSION Zibei Zhike Granules has good clinical effects on acute broncho-bronchitis.关键词
紫贝止咳颗粒/余邪恋肺证/急性气管-支气管炎Key words
Zibei Zhike Granules/Yu Xie Lian Fei/acute broncho-bronchitis分类
医药卫生引用本文复制引用
范军铭,范小会,范伏元,毛兵,郑四平,蔡鸿彦..紫贝止咳颗粒治疗急性气管-支气管炎的多中心临床观察[J].中成药,2017,39(10):2024-2029,6.基金项目
河南省中医临床学科领军人才培养计划(1403522) （1403522）
