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左半结肠术后吻合口漏预测评分系统在腹腔镜直肠癌手术中的应用价值

胡海 燕锦 刘超 徐琳 宋博 周海洋 张轲 易波 郑阳春

浙江医学2017,Vol.39Issue(17):1413-1416,1420,5.
浙江医学2017,Vol.39Issue(17):1413-1416,1420,5.DOI:10.12056/j.issn.1006-2785.2017.39.17.2017-1704

左半结肠术后吻合口漏预测评分系统在腹腔镜直肠癌手术中的应用价值

Application of colon leakage score in laparoscopic anterior resection for rectal cancer

胡海 1燕锦 2刘超 1徐琳 2宋博 1周海洋 2张轲 1易波 2郑阳春1

作者信息

  • 1. 610041成都,四川省肿瘤医院·研究所,四川省癌症防治中心
  • 2. 电子科技大学医学院
  • 折叠

摘要

Abstract

Objective To assess the application of the colon leakage score (CLS) in predicting the risk of anastomotic leakage (AL) after laparoscopic anterior resection for rectal cancer.Methods Clinical data of 268 patients with rectal cancer undergoing laparoscopic anterior resection between January 2014 and December 2016 were retrospectively reviewed.The predictive value of CLS was assessed by receiver operating characteristic curve (ROC).Logistic regression analysis was performed to determine the correlation between the CLS and the occurrence of AL.The predicted probability of AL per CLS value was calculated.Results Among 268 patients,the rate of anastomotic leakage was 5.6%(15/268).The mean CLS in the leakage group was 12.93 ± 2.12 versus 9.68 ± 3.05 in the non-leakage group (P<0.01).The area under the ROC curve (AUC) was 0.823 (95%CI:0.733-0.913).Logistic regression analysis showed an odds ratio (OR) of 1.37(95%CI:1.16-1.62,P<0.01).Both of AUC and OR indicated that the CLS was a predictor of anastomotic leakage.A CLS of 11 was used for cutoff value,with a sensitivity and specificity of 93% and 66%,respectively.Conclusion The CLS can be used to predict the risk of anastomotic leakage after laparoscopic anterior resection for rectal cancer and it may provide an indicator for clinical decision of enterostomy.

关键词

直肠肿瘤/吻合口漏/腹腔镜/预测

Key words

Rectal neoplasms/Anastomotic leakage/Laparoscopy/Predictor

引用本文复制引用

胡海,燕锦,刘超,徐琳,宋博,周海洋,张轲,易波,郑阳春..左半结肠术后吻合口漏预测评分系统在腹腔镜直肠癌手术中的应用价值[J].浙江医学,2017,39(17):1413-1416,1420,5.

基金项目

四川省科技厅资助课题(2017TD0029) (2017TD0029)

浙江医学

OACSTPCD

1006-2785

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