摘要
Abstract
Objective To analyze the association of clinical factors with disease severity and prognosis in child facial cellulitis.Methods A total of 49 children with community-acquired facial cellulites admitted in our hospital from January 2011 to January 2017 were recruited in the study.Pearson correlation analysis was used to analyze the correlation between the total duration of disease,the length of hospital stay,the length of fever and the age,the maximum temperature,white blood cell (WBC) count,C-reactive protein (CRP) value,the start time of intravenous antibiotic.T-test was used to analyze the effect of the choice of antimicrobial agents in the early course of the disease (normal β-lactam antibiotic or β-lactamase inhibitors antibiotics/vancomycin) on the total duration of disease,the length of hospital stay,the length of fever.Multiple linear regression analysis was performed with the length of hospital stay(Y) as the dependent variable,the age(X1),the maximum temperature (X2),WBC count(X3),CRP value(X4),and the start time of intravenous antibiotic(X5) as the independent variables.Results The length of fever was positively correlated with the maximum temperature,CRP value,and the start time of intravenous antibiotic (r=0.755,0.455 and 0.351,all P＜0.05),negatively correlated with the age (r=-0.304,P=0.034),and not correlated with WBC count (r=0.094,P=0.522).The length of hospital stay was positively correlated with the CRP value(r=0.442,P=0.001),and not correlated with other indicators (all P ＞0.05).There was no significance correlation between the duration of disease and other indexes(all P ＞0.05).There were no significant differences in the duration of disease,the length of hospital stay and the length of fever between patients normal β-lactam antibiotic or β-lactamase inhibitors antibiotics/vancomycin within 48h or 72h of disease onset (all P ＞0.05).The maximum temperature(X2) and the start time of intravenous antibiotic (X5) had linear regression with the length of fever(Y),and the regression equation was Y=-84.200+2.204X2+0.762X5.Conclusion The length of fever is correlated with the age,the maximum temperature,CRP value and the start time of intravenous antibiotic.The early use of antibiotics can shorten the course of community-acquired facial cellulites,and no matter the normal β-lactam antibiotic or β-lactamase inhibitors antibiotics/vancomycin are used.The maximum temperature and the start time of intravenous antibiotic have predictive significance for the length of fever.关键词
蜂窝织炎/WBC/C反应蛋白值/体温/抗菌药物Key words
Cellulitis/WBC/C-reactive protein value/Temperature/Antibiotic
