组织工程与重建外科杂志2017，Vol.13Issue(4)：201-204,4.DOI:10.3969/j.issn.1673-0364.2017.04.007
755nm皮秒翠绿宝石激光治疗黄褐斑的疗效观察
Effectiveness of Picosecond 755 nm Alexandrite Laser for the Treatment of Melasma
夏栩琼 1郑蕊 1沈征宇 1陈军1
作者信息
- 1. 200011上海市 上海交通大学医学院附属第九人民医院皮肤科
- 折叠
摘要
Abstract
Objective To evaluate the clinical efficacy,safety and recurrence rate of picosecond 755 nm alexandrite laser in the treatment of melasma.Methods All 51 patients with melasma were treated with picosecond 755 nm alexandrite laser combined with a focus lens array for 5 treatment sessions every 3 weeks.The treatment parameter:0.4 J/cm2 of fluence,8 mm of spot size,5 Hz of frequency and 550×10-12 sec of pulse duration.Patients were all followed up for 8 weeks.Outcomes assessments including photography,melasma area and severity index (MASI) score and related adverse reactions were recorded.The factors affecting the treatment were analyzed.Results The mean MASI score decreased dramatically from (12.04±6.54) to (6.82±5.63) after 5 laser treatment sessions,the decreasing ration of the MASI score was about 47.22％.But after 8-week follow up,the mean MASI score slightly increased to (7.67±5.63).No obvious side effect was observed.Through the statistical analysis,disease duration,severity,wood's lights typing,Fiztpatrick typing,and family history of melasma had impact on the prognosis of melasma.Conclusion The novel picosecond 755 nm alexandrine laser is effective and safe with lower recurrence rate in the treatment of melasma,and is worthy of promotion.关键词
皮秒翠绿宝石激光/黄褐斑/疗效评价Key words
Picosecond alexandrite laser/Melasma/Treatment assessment分类
医药卫生引用本文复制引用
夏栩琼,郑蕊,沈征宇,陈军..755nm皮秒翠绿宝石激光治疗黄褐斑的疗效观察[J].组织工程与重建外科杂志,2017,13(4):201-204,4.
