组织工程与重建外科杂志2017，Vol.13Issue(5)：248-251,4.DOI:10.3969/j.issn.1673-0364.2017.05.003
DSA引导下半导体激光联合聚多卡醇治疗儿童静脉畸形的临床观察
Application of Semiconductor Laser Combined with Polidocanol under the Digital Subtraction Angiography for the Treatment of Venous Malformations in Children
张文显 1高阳 1薛磊 1杨伊帆 1杜雅 1刘琪 1张蕴珍1
作者信息
- 1. 050030 河北省石家庄市 河北省儿童医院整形外科
- 折叠
摘要
Abstract
Objective To evaluate the effectiveness and safety of combined application of semiconductor laser and polidocanol under the digital subtraction angiography (DSA) for the treatment of venous malformations in children. Methods From August 2016 to May 2017, totally 57 patients of VMs were treated by semiconductor laser combined with polidocanol. All patients diagnosed as VM according to MRI examination and evaluation by 2 experienced physicians. All patients accepted at least once combined therapy and all the treatment were finished under the DSA. Three months after the therapy, all patients got MRI re-examination. The effectiveness is evaluated by the improvement of the lesions. Results Totally 89 times combined therapy were performed, average 1.56 ±0.12 times per child. Twelve patients were cured and 42 children got improvement of the lesion or their clinical symptoms. Three patients did not achieve any improvement. The cure rate was 21.04% and the total efficiency rate was 94.74%. The main side effects were swelling, pain and bubble. Twenty-four children appeared a local swelling of the lesion region after treatment, and improved spontaneously. Seventeen patients felt painful after the treatment and regressed in 24 hours after the treatment finished. Three children appeared a bubble at the therapy location, 2 patients regressed after 2 weeks without any special treatment, but one child appeared a secondary ulcer after the bubble was ruptured. Although the ulceration was healed after 2 weeks ' wound nursing, but the scar was left inevitably. Conclusion The combined application of semiconductor laser and polidocanol under the DSA for the treatment of venous malformations in children is safe and effective. Especially in those children who have draining veins in their lesions, the therapy is helpful in improving the therapy efficiency and reduce the treatment times.关键词
半导体激光/聚多卡醇/联合治疗/静脉畸形Key words
Semiconductor laser/Polidocanol/Combined therapy/Venous malformation分类
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张文显,高阳,薛磊,杨伊帆,杜雅,刘琪,张蕴珍..DSA引导下半导体激光联合聚多卡醇治疗儿童静脉畸形的临床观察[J].组织工程与重建外科杂志,2017,13(5):248-251,4.
