磁共振成像2017，Vol.8Issue(10)：732-736,5.DOI:10.12015/issn.1674-8034.2017.10.003
常规MRI图像纹理分析对颞叶癫痫海马硬化的诊断价值
The value of conventional MRI texture analysis in diagnosing temporal lobe epilepsy by hippocampal sclerosis
摘要
Abstract
Objective: To explore the value of conventional MRI texture analysis in diagnosing temporal lobe epilepsy due to hippocampal sclerosis. Materials and Methods: The oblique coronal T2 FLAIR images of 22 patients with temporal lobe epilepsy and hippocampal sclerosis confirmed by pathology were analyzed by using Mazda software. The feature selection methods included mutual information (MI), Fisher coefficient and classification error probability combined with average correlation coefficients (POE+ACC), Through these methods, the texture features of hippocampus were extracted. Then, four statistical methods were used to distinguish the hippocampal sclerosis side and normal side of the patients that were raw data analysis (Raw Date), the principal component analysis (PCA), linear discriminant analysis (LDA) and nonlinear discriminant analysis (NDA). The results are indicated with misclassification rate. Meanwhile, 2 neuroradiologists also reviewed the MR images of 22 patients. The differences of the results between the two analysis methods were analyzed finally. Results: The misclassification rate was the lowest (2/44, 4.55%) via the FPM selection and NDA statistical method. Furthermore, there were statistically significant differences of the misclassification rate between the texture analysis and neuroradiologists' analysis (11/44, 25%). Conclusion: Texture analysis of conventional MRI can provide reliable objective basis for the diagnosis of temporal lobe epilepsy due to hippocampal sclerosis.关键词
癫痫,颞叶/海马硬化/磁共振成像/纹理分析Key words
Epilepsy,temporal lobe/Hippocampal sclerosis/Magnetic resonance imaging/Texture analysis分类
医药卫生引用本文复制引用
马向宏,袁冠前,徐志华,杨本强..常规MRI图像纹理分析对颞叶癫痫海马硬化的诊断价值[J].磁共振成像,2017,8(10):732-736,5.基金项目
辽宁省科技计划项目(编号:2015305010)This work was part of Science and Technology Plan Project of Liaoning Province (No. 2015305010). （编号:2015305010）
