磁共振成像2017，Vol.8Issue(10)：780-784,5.DOI:10.12015/issn.1674-8034.2017.10.011
磁共振DWI、IVIM与宫颈癌病理学特征的相关性研究
Study of the correlation between DWI and IVIM and the pathology of cervical cancer
摘要
Abstract
Objective: To evaluate and contrast intravoxel incoherent motion (IVIM) and diffusion-weighted imaging (DWI) in the differentiation of cervical squamous cell carcinima and normal cervical tissue and cervical squamous cell carcinima. Materials and Methods: Collecting 9 normal people and 37 patients diagnosed with cervical squamous cell carcinoma according to surgery or biopsy with pelvic MRI routine scan sequence and IVIM sequences. In the 37 patients, including 9 high differentiation cervical squamous cell cancer, 20 medium differentiation cervical squamous cell cancer and 8 low differentiation cervical squamous cell cancer. Everyone underwent cervical magnetic resonance imaging (MRI) examination before treatment. Results:(1) The values of ADC, D in cervical squamous cell carcinoma were lower than those in normal cervical tissue, the values of D*, f in cervical squamous cell carcinoma were higher than those in normal cervical tissue, they all had obvious differences (P<0.05), the mean value of ADC had the best diagnostic efficiency. (2) The mean values of ADC and D were smaller and D* and f were bigger in the lower differentiated squamous cell carcinoma; The mean values of D between any differentiated degree differentiation cervical squamous cell carcinoma had obvious difference (P<0.001);When differentiating high from medium differentiated squamous cell carcinoma, the mean value of ADC had the best diagnostic efficiency; When differentiating poorly from medium differentiated squamous cell carcinoma, the mean value of D had the best diagnostic efficiency; The mean values of f between high and poorly differentiation cervical squamous cell carcinoma had obvious difference (P<0.05); The mean values of D* between any differentiated degree differentiation cervical squamous cell carcinoma had no obvious difference (P>0.05). Conclusion: IVIM and DWI can differentiate cervical cancer and normal cervical tissue, it is important of IVIM in distinguishing different degree of the cervical squamous carcinoma.关键词
子宫颈肿瘤/体素内不相干运动/扩散加权成像/磁共振成像/病理学Key words
Uterine cervical neoplasms/Intravoxel incoherent motion/Diffusion weighted imaging/Magnetic resonance imaging/Pathology分类
医药卫生引用本文复制引用
胡莎莎,陈小莉,刘海峰,殷亮,徐凯,雷军强..磁共振DWI、IVIM与宫颈癌病理学特征的相关性研究[J].磁共振成像,2017,8(10):780-784,5.基金项目
甘肃省兰州市城关区科研项目(编号:2016-7-10)This work was part of Chengguan District Research Projects in Lanzhou, Gansu Province (No. 2016-7-10). （编号:2016-7-10）
