摘要
Abstract
Objective To summarize the ultrasonographic characteristics of fetus with numerical abnormalities of chromosomes in the first and second trimester .Methods Fifty-three fetuses in the first and second trimester definitely diagnosed as numerical abnormalities of chromosomes were enrolled ,including 31 with 21-trisomy,12 with 18-trisomy,three with 13-trisomy,three with 45,XO,one with 47,XXX, one with 48,XXYY and two with 47,XXY.The ultrasonographic results of the fetuses were analyzed retrospectively .Results Abnormal sonographic manifestations were found in 43(81.1%) fetuses.Simple structural abnormalities were observed in 8 cases(15.1%,8/53),including three with 18-trisomy,two with 13-trisomy,one with 45,XO,one with 48,XXYY and one with 47,XXY.Structural malformation complicated with positive ultrasonographic soft markers were observed in 8 cases(15.1%,8/53),including two with 21-trisomy,five with 18-trisomy and one with 13-trisomy.Simple positive ultrasonographic soft markers were observed in 27 cases(50.9%,27/53),including 22 with 21-trisomy, two with 18-trisomy,two with 45,XO and one with 47,XXX.No abnormal ultrasonographic findings were found in 10 cases(18.9%,10/53), including seven with 21-trisomy,two with 18-trisomy and one with 47,XXY.Conclusion In the common chromosomal abnormalities ,no obvious structural abnormalities or only abnormal soft markers are manifested in most fetuses with 21-trisomy by prenatal ultrasound ,but the fetuses with 18-trisomy,13-trisomy or 45,XO can be detected by prenatal ultrasound usually because of complication with severe structural abnormalities.关键词
染色体畸形/超声检查/结构畸形/超声软指标/早孕期/中孕期/胎儿Key words
Abnormalities of chromosomes/Ultrasonography/Structural abnormalities/Ultrasonographic soft markers/First trimester/Second trimester/Fetus分类
医药卫生
