哈尔滨商业大学学报（自然科学版）2017，Vol.33Issue(5)：537-540,555,5.
微生物转化法提高甘草中甘草次酸的质量分数
Improvement of glycyrrhetinic acid yield in glycyrrhiza uralensis by microbial transformation
摘要
Abstract
A microbial transformation process was intended to be developed for improving the content of glycyrrhetinic acid from glycyrrhiza uralensis in order to provide a new method for the industrial production of glycyrrhetinic acid .Strains RE4 and RE11were selected to con-vert glycyrrhiza uralensis and the contents of glycyrrhetinic acid were improved specifically , After optimization of the process , the content of glycyrrhetinic acid in glycyrrhiza uralensis was increased to from 0.1283 mg/g in the untreated one to 3.8929 mg/g,that was the 30. 34 times higher than non-conversed samples .Meanwhile , glycyrrhetinic acid was extracted by ultrasonic extraction , and then it was isolated by the macroporous resin and silica gel co-lomn chromatography .It indicated that microbial transformation of glycyrrhiza uralensis was efficient, less the energy consumption and reduce the production cost and no noise pollution and so on .关键词
甘草/微生物转化/甘草次酸/提取Key words
glycyrrhiza uralensis/microbial transformation/glycyrrhetinic acid/extraction分类
医药卫生引用本文复制引用
王宇晴,孙雅北,矫佳陈琦,郑春英..微生物转化法提高甘草中甘草次酸的质量分数[J].哈尔滨商业大学学报（自然科学版）,2017,33(5):537-540,555,5.基金项目
哈尔滨市科技局优秀学科带头人项目(2014RFXXJ094) （2014RFXXJ094）
黑龙江省自然科学基金面上项目(H2015003) （H2015003）
