湖南中医药大学学报2017，Vol.37Issue(10)：1124-1127,4.DOI:10.3969/j.issn.1674-070X.2017.010.020
轻型慢性乙型肝炎湿热蕴结证与肝郁脾虚证肝组织纤维化分级及肝脏硬度值的比较
The Comparison of Liver Tissue Fibrosis Degree and Liver Stiffness Measurement in Mild CHB Patients with Damp-Heat Accumulation Syndrome and Liver Stagnation and Spleen Deficiency Syndrome
彭杰 1宋征福 2陈斌 1陈祥军2
作者信息
- 1. 湖南中医药大学第一附属医院肝病科,湖南 长沙 410007
- 2. 湖南中医药大学 研究生院,湖南 长沙 410007
- 折叠
摘要
Abstract
Objective To compare the difference of liver tissue fibrosis degree and liver stiffness measurement value in mild chronic hepatitis B (CHB) patients with damp-heat accumulation syndrome and liver stagnation and spleen deficiency syndrome. Methods The cilnical data of 161 mild CHB patients were retrospective analysised. Based on TCM syndrome types differentiation, the invalids were divided into damp-heat accumulation syndromes (DAS) group and liver stagnation and spleen deficiency syndrome (LSS) group. The differences of liver tissue fibrosis stage and liver stiffness measurement value were analyzed by applying propensity score matching (PSM) method (1:1). Results (1) After PSM, 116 mild CHB patients were divided into DAS group and LSS group, 58 cases in each group. The clinical demographic characteristics were not statistically signifi-cant (P>0.05). (2) The liver tissue fibrosis stage of 89.66% (104/116) mild CHB patients was S0-2, liver tissue fibrosis of DAS was significantly higher than that of LSS (P<0.05). (3) The liver stiffness measurement value of DAS group was signifi-cantly higher than that of LSS group (P<0.05). Conclusion In the eraly course of mild CHB, the liver fibrosis degree of DAS was seriouser than LSS. Startting antiretroviral treatment in mild CHB patients, the operation of TCM syndrome differentiation should be timely applied to block the progression of liver fibrosis as early as possible.关键词
慢性乙型肝炎/肝纤维化/肝硬度值/湿热蕴结证/肝郁脾虚证Key words
chronic hepatitis B/liver fibrosis/liver stiffness measurement value/damp-heat accumulation syndrome/liver stagnation and spleen deficiency syndrome分类
医药卫生引用本文复制引用
彭杰,宋征福,陈斌,陈祥军..轻型慢性乙型肝炎湿热蕴结证与肝郁脾虚证肝组织纤维化分级及肝脏硬度值的比较[J].湖南中医药大学学报,2017,37(10):1124-1127,4.
