临床神经病学杂志2017，Vol.30Issue(5)：333-336,4.
认知障碍简明评价表对帕金森病患者轻度认知功能障碍的诊断价值
Diagnostic value of cognitive-12 scale on mild cognitive impairment in Parkinson's disease patients
王谟兰 1徐俊 2朱晓峰 2徐耀 2张桁忠2
作者信息
- 1. 225001 江苏省复员退伍军人精神病医院,江苏省扬州五台山医院神经内科
- 2. 扬州大学医学院附属医院,江苏省苏北人民医院
- 折叠
摘要
Abstract
Objective To explore the diagnostic value of cognitive-12 scale ( Cog-12 scale) on mild cognitive impairment ( MCI) in Parkinson's disease ( PD).Methods Eighty-five PD patients were divided into normal cognitive function group ( 45 cases ) and mild cognitive impairment ( PD-MCI ) group ( 40 cases ) by cognitive disorder diagnostic criteria.Cog-12 scale, Montreal cognitive assessment scale (MoCA), MMSE weight tables for patient evaluation , analysis of them on PD patients with mild cognitive impairment screen .Results Compared with normal cognitive function group , the score of Cog-12 scale was significantly increased , scores of MoCA and MMSE were significantly decreased (all P<0.001).The discriminating ability of Cog-12 diagnosed MCI in PD patients was better than MoCA and MMSE (AUCCog-12 =0.958, sensitivity was 85.7%, specificity was 75%;AUCMMSE =0.798, sensitivity was 52.4%, specificity was 26.5%; AUCMoCA =0.907, sensitivity was 71.4%, specificity was 21.5%).The area under ROC curve showed that the sensitivity of Cog-12 score in predicting MCI was 85.7% when its cutoff value was 7.5.Conclusions Cog-12 scale can be effective in detecting cognitive impairment in patients with PD.It can be applied to clinical screening for cognitive dysfunction in PD patients .关键词
帕金森病/轻度认知障碍/认知障碍简明评价表Key words
Parkinson's disease/mild cognitive impairment/cognitive-12 scale分类
医药卫生引用本文复制引用
王谟兰,徐俊,朱晓峰,徐耀,张桁忠..认知障碍简明评价表对帕金森病患者轻度认知功能障碍的诊断价值[J].临床神经病学杂志,2017,30(5):333-336,4.
