临床眼科杂志2017，Vol.25Issue(5)：416-418,3.DOI:10.3969/j.issn.1006-8422.2017.05.010
白内障患者房水与血清中IL-17和MMP-2表达水平的变化
Changes of IL-17 and MMP-2 in aqueous humor and serum of patients with cataract
唐靖 1卡米力·努尔2
作者信息
- 1. 845350 新疆克孜勒苏自治州人民医院眼科
- 2. 新疆喀什地区第二人民医院眼科
- 折叠
摘要
Abstract
Objective To investigate the clinical significance of interleukin -17(IL-17)and matrix metalloprotei-nase -2(MMP-2)concentration in aqueous humor and serum of patients with cataract.Methods 90 cataract patients who were treated in our hospital between January 2016 and January 2017 were selected,and 80 healthy volunteers were enrolled as control.Enzyme-linked immunosorbent assay(ELISA)was used to detect serum IL-17 and MMP-2 levels and correlation analysis of serum and aqueous humor MMP-2 and IL-17 were conducted.Results Before treatment,both IL-17 and MMP-2 weresignificantly higher in serum and anterior chamber in cataract patients than in normal subjects(all P<0.05).Pear-son analysis showed that serum and aqueous humor IL-17 levels were positively correlated to corresponding MMP-2 levels in cataract patients(both P<0.05)Conclusions IL-17 and MMP-2 are highly expressed in the aqueous humor and serum of cataract patients,which may be closely related to the inflammatory reactions in these patients,and both can be actively participated in the occurrence and development of cataract.关键词
白内障/房水/血清/白介素-17/基质金属蛋白酶-2Key words
Cataract/Aqueous humor/Serum/Interleukin-17/Matrix metalloproteinase-2引用本文复制引用
唐靖,卡米力·努尔..白内障患者房水与血清中IL-17和MMP-2表达水平的变化[J].临床眼科杂志,2017,25(5):416-418,3.
