热带作物学报2017，Vol.38Issue(7)：1216-1223,8.DOI:10.3969/j.issn.1000-2561.2017.07.007
油茶籽油及枯饼提取物的抗肿瘤活性研究
Anticancer Activities of the Extract Fromoils and Cakes of Camellia spp.
摘要
Abstract
The anticancer activities of oils and cakes of Camellia spp. were detected by MTT in this paper. And the total phenolics and total flavonoids were measured by Folin-Ciocalteu reagent and aluminium chloride reagent, respectively. The results showed that the content of total phenolic (151.04μg/g) and total flavonoid (1.37 mg/g) of the oil produced by stir-frying and squeezing from Qionghai exceeded those of the other samples. The total phenol content in seven cakes of Camellia spp. had no significant difference, and the total flavonoid content of the cake produced by steaming and squeezing from Putian was higher than other samples. The specific anticancer activities were clear from the oils and cakes of Camellia spp.. And their antiproliferative activities to lung cancer (Lewis), melanoma (B16) and breast cancer (SCC891) cells in a range of concentrations from 1 to 50μg/mL were increased in dose-dependent manner. Therefore, it had potential medical values and economic benefits to develop the anticancer effect of Camellia spp..关键词
油茶/总酚/总黄酮/抗肿瘤活性Key words
Camellia spp./total phenolics/total flavonoids/anticancer activities分类
医药卫生引用本文复制引用
叶洲辰,吴友根,张军锋,胡新文,于靖,周开兵,林尤奋,王健,陈健妙..油茶籽油及枯饼提取物的抗肿瘤活性研究[J].热带作物学报,2017,38(7):1216-1223,8.基金项目
2017年海南省重大科技计划项目 "海南油茶优质高产关键技术及加工产品研发"(No. ZDKJ2017004) （No. ZDKJ2017004）
海南省重点研发专项(No. ZDYF2016157, 2015ZY24) （No. ZDYF2016157, 2015ZY24）
2015和2016年海南大学地方服务项目(No. HD-KYH-2015105, PT45523010001013004). （No. HD-KYH-2015105, PT45523010001013004）
