山东医药2017，Vol.57Issue(39)：19-22,4.DOI:10.3969/j.issn.1002-266X.2017.39.005
中枢、非中枢原因心脏骤停患者心肺复苏后72 h内循环功能对比观察
Comparative observation of circulatory function within 72 h after restoration of spontaneous circulation between patients with cardiac arrest caused by central nervous system impairment or non-CNS causes
摘要
Abstract
Objective To compare the changes of circulatory function within 72 h after restoration of spontaneous cir-culation (ROSC)between patients with cardiac arrest caused by central nervous system (CNS)impairment or non-CNS causes. Methods Twenty patients experiencing ROSC after cardiac arrest caused by CNS impairment (group A)and 17 patients with non-CNS causes (group B)were selected. We collected the heart rate,blood pressure,urine volume,the dif-ferent sorts of vasoactive drugs and so on at different points of time (admission to hospital,6 h,12 h,24 h,36 h,48 h and 72 h)after hospitalization. Meanwhile the arterial blood gas analysis results (including serum lactate )were collect-ed. Then the lactate clearance rate and oxygenation index (OI)were calculated. Results The blood lactate concentration tended to be normal at 72 h after ROSC started in all patients,and the lactate clearance rate was found the highest in the first 6 h. The lactate clearance rate of the first 6 h,and the first 24 h in the group A were found lower than those of group B,and the rate in 36-48 h after ROSC of group A was higher than that of group B (all P < 0. 05). The urine output volume of group A was significantly higher than that of the group B at 6-12 h,12-24 h,24-36 h,36-48 h,and 48-72 h (all P <0. 05 ). Twelve patients in group A still took vasoactive drugs,but only four patients in the group B took at 72 h,the per-centage of using vasoactive drugs of group A was higher than that of the group B (P < 0. 05). Conclusions The most sig-nificant improvement of circulation after ROSC within 72 h in patients with cardiac arrest is in the early stage. The circula-tion recovery of cardiac arrest patients with CNS impairment is relatively backward.关键词
心脏停搏/心肺复苏术/血液循环/心脏骤停后综合征/乳酸清除率/血管活性增效剂Key words
heart arrest/cardiopulmonary resuscitation/blood circulation/post cardiac arrest syndrome/lactic acid clearance rate/vasoconstrictor agents分类
医药卫生引用本文复制引用
黄锡通,李结华..中枢、非中枢原因心脏骤停患者心肺复苏后72 h内循环功能对比观察[J].山东医药,2017,57(39):19-22,4.基金项目
安徽省软科学研究专项基金项目(1607a0202044). （1607a0202044）
