天然产物研究与开发2017，Vol.29Issue(9)：1475-1478,4.DOI:10.16333/j.1001-6880.2017.9.004
通过Baylis-Hillman反应构筑Malyngamide K关键中间体的研究
Synthesis of Key Intermediate of Malyngamide K via Baylis-Hillman Reaction
摘要
Abstract
Malyngamide K is a typical example of malyngamides with both cyclohexenone and allyl chloride moieties.The construction of its amine carbon skeleton is very important for the design of general synthetic route of those malyngamides.In this work,the amine carbon skeleton of malyngamide K was constructed between ethanol amine (2) and cyclohexanone (5) by Baylis-Hillman reaction,which provides a new synthetic route for those malyngamide analogues with both cyclohexenone and allyl chloride substructures.关键词
有机化学/Baylis-Hillman反应/合成/malyngamide KKey words
organic chemistry/Baylis-Hillman reaction/synthesis/malyngamide K分类
化学化工引用本文复制引用
段姝慧,施群,张军涛..通过Baylis-Hillman反应构筑Malyngamide K关键中间体的研究[J].天然产物研究与开发,2017,29(9):1475-1478,4.基金项目
湖北省自然科学基金(2016CFB299) （2016CFB299）
