天然产物研究与开发2017，Vol.29Issue(9)：1608-1616,9.DOI:10.16333/j.1001-6880.2017.9.026
1,3-二炔类天然产物的合成及生物活性研究进展
Review on the Syntheses and Biological Activity of 1,3-Diyne Natural Products
摘要
Abstract
Polyacetylenes,a class of natural products,widely exist in the nature.Due to their unique structure and pharmacological activity,polyacetylenes have evoked a great deal of interest in chemists and biologists worldwide.Currently,the research of polyacetylenes mainly focused on 1,3-diyne natural products which possess diverse structural scaffold and biological activity such as anticancer,neurotoxicity,anti-inflammatory activity and immune inhibitory activity.However,the progressive review about 1,3-diyne natural products has not been reported so far.In this review,the research progress in recent years concerningthe synthesis and pharmacological activities of 1,3-diyne natural products was systematically summarized,in order to provide ideas and methods for the development and utilization of 1,3-diyne natural products.关键词
1,3-二炔类天然产物/有机合成/生物活性/毒性Key words
1,3-diyne natural products/organic synthesis/biological activity/toxicity分类
医药卫生引用本文复制引用
苗延红,马开庆,秦雪梅..1,3-二炔类天然产物的合成及生物活性研究进展[J].天然产物研究与开发,2017,29(9):1608-1616,9.基金项目
国家自然科学基金青年项目(21402111) （21402111）
山西省青年科技研究基金(2015021039) （2015021039）
山西省回国留学人员科研资助项目(2015-020) （2015-020）
