医疗卫生装备2017，Vol.38Issue(7)：63-66,4.DOI:10.7687/j.issn1003-8868.2017.07.063
磁共振对非酒精性脂肪肝定量诊断的初步研究
Preliminary study on quantitative assessment of nonalcoholic fatty liver disease by MRI
尹子铭 1石建军 1续秋艳 1巫志勇1
作者信息
- 1. 102300北京,北京市门头沟区医院影像中心
- 折叠
摘要
Abstract
Objective To discuss the feasibility for quantitative assessment of nonalcoholic fatty liver disease by sequence of diffusion weighted imaging and hydrogen proton magnetic resonance spectroscopy.Methods Thirty patients with NAFLD and twenty-six normal volunteers were enrolled in an experiment group,and 25 healthy volunteers were selected into a control group.All the patients and volunteers underwent CT and MRI examinations.With the ratio of liver-to-spleen CT value as reference standard,the correlation and difference of ADC value,value of water peak,the area under water peak,values of lipid peak and area under lipid peak and fat fraction were measured and compared between the two groups.Results There was positive significant correlation between ratio of liver-to-spleen CT value and ADC value (r=0.92,P＜0.05),and negative significant correlation between ratio of liver-to-spleen CT value and lipid peak and area of lipid peak (r=-0.91 and r=-0.96,respectively;all P＜0.05),there was significant negative correlation between ADC value and lipid peak and area of lipid peak (r=-0.91,P＜0.05),and ADC value,the values of water peak,lipid peak and area under peak and fat fraction were different between the two groups (P＜0.05).Conclusion There is significant correlation and difference between DWI and 1H-MRS in evaluating NAFLD,which has the potential to quantitatively diagnose the severity and degree of fatty liver.关键词
扩散加权成像/磁共振波谱/脂肪肝/磁共振成像Key words
diffusion weighted imaging/magnetic resonance spectroscopy/fatty liver/magnetic resonance imaging分类
医药卫生引用本文复制引用
尹子铭,石建军,续秋艳,巫志勇..磁共振对非酒精性脂肪肝定量诊断的初步研究[J].医疗卫生装备,2017,38(7):63-66,4.
