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认知储备在大脑老化中的研究进展

林岚 张柏雯 王婧璇 高宏建 吴水才

医疗卫生装备2017,Vol.38Issue(9):93-98,6.
医疗卫生装备2017,Vol.38Issue(9):93-98,6.DOI:10.7687/j.issn1003-8868.2017.09.093

认知储备在大脑老化中的研究进展

Research advance of cognitive reserve in brain aging

林岚 1张柏雯 1王婧璇 1高宏建 1吴水才1

作者信息

  • 1. 100124北京,北京工业大学生命科学与生物工程学院
  • 折叠

摘要

Abstract

The current proxy indicators and quantitative strategy were summarized for cognitive reserve,the findings of cognitive reserve was discussed then in brain aging and Alzheimer's disease,and some future research directions were presented about cognitive reserve.The reserve of brain explains the disjunction between clinical symptoms and the degree of brain damage,whereby some people can tolerate more of age-related or Alzheimer's disease pathology than others and maintain brain function.The cognitive reserve hypothesis has been widely used in epidemiological and neuroimaging studies,but it lacks a unified quantitative indicator.The future research of cognitive reserve should be focused on the development of quantitative indicators that cover a variety of potential factors dynamically.

关键词

认知储备/脑储备/大脑老化/代理指标/定量测量/阿尔茨海默病

Key words

cognitive reserve/brain reserve/brain aging/proxy indicator/quantitative measurement/AD

分类

医药卫生

引用本文复制引用

林岚,张柏雯,王婧璇,高宏建,吴水才..认知储备在大脑老化中的研究进展[J].医疗卫生装备,2017,38(9):93-98,6.

基金项目

国家科技支撑计划课题(2015BAI02B03) (2015BAI02B03)

国家自然科学基金(71661167001) (71661167001)

医疗卫生装备

OACSTPCD

1003-8868

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