中国药业2017，Vol.26Issue(21)：39-41,3.DOI:10.3969/j.issn.1006-4931.2017.21.014
喜普妙与路优泰对躯体化抑郁症的疗效及脑电图研究
Clinical Efficacy of Cipramil and Neurostan for Treating Somatization Depression and Its Effect on EEG Changes
摘要
Abstract
Objective To observe the clinical efficacy of Cipramil and Neurostan in the treatment of somatization depression and the changes of electroencephalogram ( EEG ) before and after treatment. Methods Totally 60 patients with somatization depression from Jan-uary 2015 to February 2017were selected and randomly divided into the treatment group A ( group A, treated with Neurostan ) , the treatment group B ( group B, treated with Cipramil ) and the control group ( treated with simple psychotherapy ) . The Hamilton Depression Scales ( HAMD ) scores and EEG changes before and after treatment were compared. Results After 12 weeks, The HAMD scores of group A and group B were (10. 40 ±5. 86) points and (8. 20 ±5. 24) points, respectively, which were significantly lower than (23. 60 ±3. 57) points in the control group ( P < 0. 01 ) . After treatment, the abnormal rate of EEG in control group was 65. 00%, which was signifi-cantly higher than 25. 00% in the treatment group ( P < 0. 01 ) . Conclusion Both of Cipramil and Neurostan in the treatment of somati-zation depression have good effect, but compared with Neurostan, Cipramil works faster, at the same time the application of EEG exami-nation in the diagnosis of depression has certain clinical significance.关键词
抑郁症/喜普妙/路优泰/脑电图Key words
depression/Cipramil/Neurostan/electroencephalogram分类
医药卫生引用本文复制引用
王彩宁,温爱萍,杨梅柳,田欣,张志全,齐晓华,虞武..喜普妙与路优泰对躯体化抑郁症的疗效及脑电图研究[J].中国药业,2017,26(21):39-41,3.基金项目
河北省卫生计生委"河北省2017年度医学科学研究重点课题计划(唐山部分)"[ 20171391 ]. （唐山部分）
