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小剂量阿司匹林联合低分子肝素钠对复发性流产患者预后的影响

吴淑芬 黄文华 张秀丽

中国药业2017,Vol.26Issue(21):64-66,3.
中国药业2017,Vol.26Issue(21):64-66,3.DOI:10.3969/j.issn.1006-4931.2017.21.023

小剂量阿司匹林联合低分子肝素钠对复发性流产患者预后的影响

Effect of Low Dose Aspirin Combined with Low Molecular Weight Heparin on Prognosis of Patients with Recurrent Spontaneous Abortion

吴淑芬 1黄文华 2张秀丽1

作者信息

  • 1. 漯河医学高等专科学校第二附属医院,河南漯河 462300
  • 2. 河南省漯河市郾城区人民医院,河南漯河 462300
  • 折叠

摘要

Abstract

Objective To investigate the effect of low dose aspirin combined with low molecular weight heparin ( LMWH ) on the progno-sis of patients with recurrent spontaneous abortion. Methods Totally 120 patients with recurrent spontaneous abortion admitted to the hospital from January 2014 to January 2017 were selected and divided into the control group and the observation group by the random number table method, 60 cases in each group. The control group was treated with LMWH, while the observation group was treated low dose aspirin combined with LMWH. Results After treatment, compared with the control group, the increase of PT, TT and APTT levels and the decrease of FIB level were significantly greater in the observation group after treatment ( P < 0. 05 ) . The levels of PLT in the two groups were significantly decreased after treatment ( P < 0. 05 ) , but there was no significant difference between the two groups ( P > 0. 05 ) . The live birth rate of the observation group was 81. 67%, which was significantly higher than 61. 67% of the control group ( P < 0. 05 ) . Conclusion Low dose aspirin combined with LMWH can effectively improve the prognosis of patients with recurrent spontaneous abortion.

关键词

阿司匹林/小剂量/低分子肝素/复发性流产/预后

Key words

aspirin/low dose/low molecular weight heparin/recurrent spontaneous abortion/prognosis

分类

医药卫生

引用本文复制引用

吴淑芬,黄文华,张秀丽..小剂量阿司匹林联合低分子肝素钠对复发性流产患者预后的影响[J].中国药业,2017,26(21):64-66,3.

中国药业

OACSTPCD

1006-4931

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