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曲伏前列素滴眼液治疗原发性开角型青光眼49例疗效观察

姚鹏 刘洁 杨惠婷

中国药业2017,Vol.26Issue(21):66-68,3.
中国药业2017,Vol.26Issue(21):66-68,3.DOI:10.3969/j.issn.1006-4931.2017.21.024

曲伏前列素滴眼液治疗原发性开角型青光眼49例疗效观察

Clinical Observation Travoprost Eye Drops for Treating Primary Open-Angle Glaucoma in 49 Cases

姚鹏 1刘洁 2杨惠婷1

作者信息

  • 1. 苏州大学附属理想眼科医院,江苏苏州 215000
  • 2. 牡丹江医学院附属红旗医院,黑龙江牡丹江 157011
  • 折叠

摘要

Abstract

Objective To investigate the clinical effect of Travoprost Eye Drops for treating primary open-angle glaucoma. Methods Totally 98 patients with primary open-angle glaucoma from January 2016 to January 2017 in our hospital were divided into the control group and the observation group according to the random number table method. The control group was given Timolol Eye Drops, 1 time each morning and evening, 1 drop each time. The observation group was given Travoprost Eye Drops, 1 time in the evening, 1 drop each time. Results The total effective rate of the observation group was 95. 92%, which was significantly higher than 79. 59% of the control group ( P < 0. 05 ) . The control group had 3 cases of bradyarrhythmia, 2 cases of stabbing pain on eyes, 3 cases of burning pain on the ocular surface, 2 cases of transient dizziness, the incidence rate was 20. 41%, only 2 cases of conjunctival congestion in the observation group, the incidence rate was 4. 08%, which was significantly lower than 20. 41% of the control group ( P < 0. 05 ) . The time of recovery to normal pressure and the disappearance time of conscious symptoms of the observation group were significantly shorter than those of the control group ( P < 0. 05 ) . There was no significant difference in intraocular pressure ( IOP ) level between the two groups before treatment, 2 weeks after treatment and 4 weeks after treatment ( P > 0. 05 ) , after 8 weeks of treatment, the IOP level of the observation group was significantly lower than that of the control group ( P < 0. 05 ) . Conclusion Travoprost Eye Drops is effective in the treatment of primary open-angle glaucoma, it can effectively reduce IOP level, improve clinical symptoms, shorten the course of treatment with less adverse reactions and high safety.

关键词

曲伏前列素滴眼液/原发性开角型青光眼/临床疗效

Key words

Travoprost Eye Drops/primary open-angle glaucoma/clinical effect

分类

医药卫生

引用本文复制引用

姚鹏,刘洁,杨惠婷..曲伏前列素滴眼液治疗原发性开角型青光眼49例疗效观察[J].中国药业,2017,26(21):66-68,3.

中国药业

OACSTPCD

1006-4931

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