摘要
Abstract
Objective To investigate the clinical manifestations, mechanism and prognosis of artery embolization resulting from cosmetic facial filler injections. Methods Ten patients with artery embolization caused by cosmetic facial filler injections in Beijing Tongren Hospital from January 2013 to August 2016 were included consecutively. The clinical data including filler materials, injection sites, best-corrected visual acuity (BCVA), associated ocular and neurological manifestations, fundus fluorescein angiography (FFA), brain magnetic resonance imaging (MRI) were analyzed. Results Among 10 cases, 8 cases had ophthalmic artery occlusion (OAO), and 2 cases had central retinal artery occlusion (CRAO). Among which, 2 cases had ophthalmic artery occlusion accompanied with cerebral infarction (CI), and 3 cases had ophthalmic artery occlusion accompanied with ophthalmoplegia. Injection material included hyaluronic acid (6 cases), autologous fat (3 cases), and collagen (1 case). Injection sites were frontal area (3 cases), nose area and nasal area (2 cases), nasolabial area (2 cases), glabellar area (2 cases), and periocular area (1 case). Two cases with autologous fat injections had combined CI. The initial and finial BCVA of all cases had no light perception. Conclusion Cosmetic facial filler injections can cause artery embolization. Under the pressure of injection, the injectant may get into the orbital artery and retrograde to the ophthalmic artery and its branches, which resulting in blindness. In some cases, retrograde artery embolism can causes CI. The incidence of CI was higher with autologous fat injection than hyaluronic acid injection. The visual outcome of iatrogenic retinal artery occlusion was poor, so that strategies aimed at preventing were essential.关键词
面部注射填充/动脉栓塞/眼动脉阻塞/脑梗死Key words
Cosmetic facial filler injection/Artery embolization/Ophthalmic artery occlusion/Cerebral infarction
