中国卒中杂志2017，Vol.12Issue(10)：911-915,5.DOI:10.3969/j.issn.1673-5765.2017.10.006
扩大的血管周围间隙与脑梗死自发性出血转化的相关性
Correlation between Enlarged Perivascular Spaces and Spontaneous Hemorrhagic Transformation of Cerebral Infarction
摘要
Abstract
Objective To analyze the influence of enlarged perivascular spaces (EPVS) on spontaneous hemorrhagic transformation (HT) of cerebral infarction. Methods The clinical data of 412 patients with acute ischemic stroke who were treated in Nanhai Hospital of Southern Medical University during Dec. 2014 to Dec. 2016 were collected. Based on the magnetic resonance imagine (MRI) results, the patients were divided into two groups: with EPVS groups and without EPVS groups. Baseline characteristics, the occurrence of HT were compared. Single factor and multi-factors analysis were made to show the factors that were significantly associated with EPVS. Then, the patients were divided into two groups: with HT groups and without HT groups. Single factor and multi-factors logistic regression analysis were made to study on EPVS and various kinds of risk factors as well as the influence demographic characteristics on HT in patients with ischemic stroke. Results The baseline data comparison showed, compared to patients without EPVS, patients with EPVS were older, more likely with the history of stroke, more likely with leukoaraiosis and more likely with HT. Single factor analysis showed that there were significant difference in age, stroke recurrence, leukoaraiosis and HT. Multi-factors logistic regression analysis showed that HT and leukoaraiosis were significantly associated with EPVS. The analysis of HT showed that there were significant difference in arterial fibrillation, uses of anticoagulant drug, EPVS, large size of infraction,uric acid level and activated partial thromboplastin time (APTT), and EPVS, size of infraction and APTT level were risk factors for HT.关键词
扩大的血管周围间隙/脑梗死/自发性出血转化Key words
Enlarged perivascular spaces/Stroke/Hemorrhagic transformation引用本文复制引用
欧茹,李飞,利玉欢,潘志信,唐亚梅..扩大的血管周围间隙与脑梗死自发性出血转化的相关性[J].中国卒中杂志,2017,12(10):911-915,5.基金项目
国家自然科学基金(81471249,81622041)广东省自然科学基金(2014A030313120)佛山市卫计局科研立项(20160216) （81471249,81622041）
