中国卒中杂志2017，Vol.12Issue(10)：921-928,8.DOI:10.3969/j.issn.1673-5765.2017.10.008
计算机模拟训练对血管性认知功能障碍的干预效果研究
The Intervention Effect Study on Computer Simulated Training in Vascular Cognitive Impairment
摘要
Abstract
Objective To explore the effect of computer simulated training on cognition in patients with vascular cognitive impairment (VCI), so as to provide effective treatment for patients with VCI. Methods A total of 80 patients diagnosed with VCI in Department of Neurology of the hospital during October 2015 to November 2016 were enrolled in this study. The patients were randomized into control (n=30) and intervention (n=50) group at a ratio of 3:5. All patients were evaluated by the Montreal Cognitive Assessment (MoCA) and computer cognitive evaluation visual attention, reasoning, spatial imagination, calculation, speech memory, reading, word recognition, immediate-recall of pictures and execution ability under the guide of experienced neurologists. The control group only received conventional drug therapy. On the basis of conventional drug therapy, the intervention group received computer simulated training for a period of 30 to 60 days by trained neurologists, 1 h per time. Both groups received multidimensional recognition evaluation after 30 times of exercise. The intervention effect including visual attention, reasoning, spatial imagination, calculation, speech memory, reading, word recognition, immediate-recall of pictures and execution ability were observed. Results Analysis the basic data found that gender, age, education level of the two groups of patients were of no significant difference. The control and intervention groups did not differ on baseline cognition abilities. In MoCA scale, despite of the direction ability had no obvious change, the other cognitive sub-items were improved after computer simulated training in treatment group (P<0.05) and 9 sub-items all got improved (P<0.05). In addition to the reasoning (P=0.06) and speech memory abilities (P=0.01) decreased of the control group, the other cognitive sub-items had no obvious change. Compared with control group, computer simulated training led improvement in visual attention, reasoning, spatial imagination, calculation, speech memory, reading, word recognition, and immediate-recall of pictures and execution ability (P<0.05). Conclusion Computer-based cognitive function training can improve vascular cognitive impairment in different degrees, including visual attention, reasoning, spatial imagination, calculation, speech memory, reading, word recognition, immediate-recall of pictures and execution ability, which provides a new mean of intervention for VCI.关键词
血管性认知功能障碍/计算机模拟训练/多维认知评估Key words
Vascular cognitive impairment/Computer simulation training/Multidimensional cognitive evaluation引用本文复制引用
宇佳利,尹世敏,卢燕,徐芳,王秋佳,王磊..计算机模拟训练对血管性认知功能障碍的干预效果研究[J].中国卒中杂志,2017,12(10):921-928,8.基金项目
全军"十二五"科研课题(D101100050010042) （D101100050010042）
