摘要
Abstract
Objective To investigate the relationship between pathological classification of thymoma and myasthenia gravis (MG).Methods The pathological types and clinical manifestations of 468 patients with thymoma receiving thymectomy in the First Affiliated Hospital of Soochow university from September 2005 to September 2015 were retrospectively reviewed.The correlation of thymoma type with gender,age,MG and postoperative myasthenia crisis were analyzed.Results The complication rate of MG was 33.3％ in 468 patients with thymoma.The number of pathological classification of A+AB,B1,B2,B3,and C thymoma were 195,86,84,86 and 15 cases.The pathological classification of thymic tumor was significantly correlated with MG (P＜0.05) and negatively correlated with age (r=-0.13,P＜0.05),but not correlated with the gender (P ＞0.05).The incidence of postoperative myasthenia crisis was 25.6％ in thymoma patients with MG.There were no significant differences in the incidence of postoperative myasthenia crisis among A+AB,B1,B2,B3 and C types (P＞0.05),while the incidence in type B (including B1,B2 and B3 type) was significantly higher than that of type A+AB (P＜0.05).Conclusion The pathological classification of thymic tumor is associated with age,MG and postoperative myasthenia crisis,which may be of clinical predicting value.关键词
胸腺瘤/病理分型/重症肌无力/肌无力危象Key words
Thymoma pathology/Myasthenia gravis/Myasthenia crisis
