中药材2017，Vol.40Issue(6)：1322-1325,4.DOI:10.13863/j.issn1001-4454.2017.06.018
灰褐纹口蘑发酵液的化学成分研究
Chemical Constituents from Cultures of the Tricholoma portrntosum
摘要
Abstract
Objective:To isolate and identify the chemical constituents from the cultures of the Tricholoma portrntosum.Methods:Chromatographic separation techniques such as silica gel chromatography,Rp-18 chromatography and Sephadex LH-20 were used for the isolation and purification.The structures of the chemical constituents were identified on the basis of mass spectrometry,NMR spectroscopy techniques.Results:Twelve compounds were isolated from the cultures of Tricholoma portrntosum,and their structures were identified as 2,6,10-trimethyldodeca-6,11-dien-1,10-diol (1),6-hydroxy-2,6-dimethyl-7-octenoic acid(2),(3S)-3,7,11-trimethyldodeca-6,10-dien-1,2,3-triol (3),4,8-dimethyl-docadiene-4,9-dien-1,8-diol (4),3,10-epoxy-3,7,11-trimethyldodeca-1,6-dien-11-ol (5),Cyclo (D)-Pro-(D)-Leu (6),(22E,24R)-5α,8α-epidioxy-ergosta-6,22-dien-3β-ol (7),(22E,24R)-ergosta-5,7,22-trien-3β-ol (8),(22E,24R)-ergosta-7,22-dien-3β,5 α,6β-triol (9),(22E,24R)-ergosta-4,6,8 (14),22-tetraen-3-one (10),5-hydroxymethyl-2-furancarboxaldehyde (11) and 4-hydroxyphenethyl alcohol (12).Conclusion:Compound 1 is a new compound,compounds 2 ～ 5 are isolated from this genus for the first time,and all the compounds are isolated from this fungus for the first time.关键词
灰褐纹口蘑/化学成分/2,6,10-trimethyldodeca-6,11-dien-1,10-diolKey words
Tricholoma portrntosum(Fr.) Ouél./Chemical constituent/2,6,10-trimethyldodeca-6,11-dien-1, 10-diol分类
医药卫生引用本文复制引用
姚星宇,牛婉蓉,崔秀明,刘阳,杨晓艳,刘吉开..灰褐纹口蘑发酵液的化学成分研究[J].中药材,2017,40(6):1322-1325,4.基金项目
国家自然科学基金(21562029) （21562029）
昆明理工大学分析测试基金(2016T20130214) （2016T20130214）
