中药材2017，Vol.40Issue(6)：1345-1347,3.DOI:10.13863/j.issn1001-4454.2017.06.023
黄精乙酸乙酯部位的化学成分研究
Chemical Constituents of Ethyl Acetate Extract from the Rhizomes of Polygonatum sibiricum
摘要
Abstract
Objective:To determine the chemical constituents of ethyl acetate extract from the rhizomes of Polygonatum sibiricum.Methods:Isolation and purification were carried out by various chromatographic techniques,such as silica gel,SePhadex LH-20,and preparative HPLC,and their structures were elucidated by physic-chemical properties and spectral analysis.Results:Thirteen compounds were isolated from Polygonatum sibiricum,and characterized as polygonatine A (1),silvaticol (2),5-hydroxy-7-methoxy-4,6-dimethyl-2-benzofuranone (3),L-pyroglutamic acid methyl ester (4),L-pyroglutamic acid (5),5-hydroxyl-2-hydroxymethylpyridine (6),p-hydroxybenzaldehyde (7),p-hydroxybenzoic acid (8),pinoresinol (9),syringaresinol (10),5-hydroxymethylfurfural (11),β-sitosterol (12) and daucosterol(13).Conclusion:Compounds 2 ～ 6 are first isolated from this genus,and compounds 2 ～9 are isolated from this plant for the first time.关键词
黄精/乙酸乙酯部位/化学成分Key words
Polygonatum sibiricum Delar.ex Redoute/Ethyl acetate extract/Chemical constituents分类
医药卫生引用本文复制引用
陈辉,顾念念,郝志友,孙彦君,张艳丽,郑晓珂,冯卫生..黄精乙酸乙酯部位的化学成分研究[J].中药材,2017,40(6):1345-1347,3.基金项目
郑州市普通科技攻关计划项目(131PPTGG417-2) （131PPTGG417-2）
河南中医药大学博士科研基金(BSJJ2012-02) （BSJJ2012-02）
