分析测试学报2017，Vol.36Issue(8)：1055-1060,6.DOI:10.3969/j.issn.1004-4957.2017.08.020
生物膜层干涉技术在生物分子分析和检测中应用的研究进展
Research Progress in Application of Biolayer Interferometry in Analysis and Detection of Biomolecules
摘要
Abstract
Biolayer interferometry is an optical system that monitors interactions between biological materials and detects biological materials rapidly for lable-free.Due to its advantages of real-time,rapidness and low sample consumption,biolayer interferometry has been gradually used for detecting interactions between proteins,peptides,nucleic acids,small molecules,and/or lipids.Furthermore,biolayer interferometry could also provide a solid foundation in rapid detection field because of its low sample consumption and strong specificity.In this article,the principle of biolayer interferometry is discussed,and two major application areas including kinetic analysis and rapid detection are investigated and reviewed.The development trend and future application of biolayer interferometry for measuring biological materials are also prospected.关键词
生物膜层干涉技术/动力学分析/快速检测/综述Key words
biolayer interferometry/kinetic analysis/rapid detection/review分类
化学化工引用本文复制引用
杨国泰,吴鑫,李福来,王辰时,何丽华,许恒毅..生物膜层干涉技术在生物分子分析和检测中应用的研究进展[J].分析测试学报,2017,36(8):1055-1060,6.基金项目
江西省青年科学家(井冈之星)培养对象项目(2014BCB23004) （井冈之星）
江西省食品药品监督管理局科技计划(2015SP13) （2015SP13）
