影像科学与光化学2017，Vol.35Issue(6)：771-779,9.DOI:10.7517/j.issn.1674-0475.2017.05.013
用于检测三苯基膦的一种新型“点亮”型荧光探针
A Novel Turn-on Fluorescent Probe for Triphenylphosphine
摘要
Abstract
Triphenylphosphine (PPh3) is an important organic substance and extraordinary for its nucleophilicity and reducing character.It is widely used in the synthesis of organic and organometallic compounds.The extensive use of PPh3 is inevitable to cause phosphorous pollution to the environment and would pose a potential danger to human health.An effective and convenient detection method of PPh3 is fairly desirable.Herein,a novel selective and sensitive off-on fluorescent probe for PPh3 mimicking Staudinger ligation was developed.The design concept was to use a 2-azidophenylacetic ester of fluorescein to react with PPh3 to undergo a rapid intramolecular acyl transfer through aza-ylide intermediate to release the fluorophore.The probe shows highly selective response to PPh3 in water containing 0.5 ％ DMSO.The probe is promising for the quantitative detection of PPh3 with linear response from 1 × 10-7 mol/L to 8 × 10-7 mol/L with a detection limit of 10 nmol/L.The sensitive detection of PPh3 can be viewed in water solutions with "naked eye".关键词
荧光素/荧光探针/荧光增强型响应/三苯基膦/Staudinger连接Key words
fluorescein/fluorescent probe/turn-on fluorescent response/triphenylphosphine/Staudinger ligation引用本文复制引用
黄振涛,王楠楠,张健,赵伟利..用于检测三苯基膦的一种新型“点亮”型荧光探针[J].影像科学与光化学,2017,35(6):771-779,9.基金项目
国家自然科学基金(21372063)资助 （21372063）
This research was supported by NSFC(21372063). （21372063）
