影像科学与光化学2017，Vol.35Issue(6)：780-787,8.DOI:10.7517/j.issn.1674-0475.2017.05.004
双靶向CdTe量子点的制备及其在细胞标记中的应用
The Preparation of Dual Targeting CdTe Quantum Dots and Its Application in Cells Labeling
摘要
Abstract
The pH sensitive CdTe quantum dots (QDs) were prepared with thioglycolic acid (TGA) and mercapto-acetohydrazide (TGH) as the stabilizers.After being conjugated with antibody,the prepared CdTe QDs has both functions of pH sensitivity and immune recognition.The results of fluorescence luminescence (FL),transmission electron microscopy (TEM) and cells labeling imaging showed that antibody was successfully conjugated on the surface of CdTe QDs.The prepared dual targeting QDs can be used to identify the acidic interstitial extracellular environment and label tumor cells specifically.关键词
CdTe量子点/酸度敏感性/免疫靶向Key words
CdTe quantum dots/pH sensitivity/immune recognition引用本文复制引用
杨冬芝,王文文,杜岩,纪海侠..双靶向CdTe量子点的制备及其在细胞标记中的应用[J].影像科学与光化学,2017,35(6):780-787,8.基金项目
国家自然科学基金(81201696)、江苏省自然科学基金(BK20161173)、国家大学生创新创业训练计划(20131031300)和江苏省高等学校大学生实践创新训练计划项目(201310313004Z) （81201696）
