摘要
Abstract
Objective To investigate the value of 320-detector row CT perfusion imaging in acute cerebral infarction.Methods CT perfusion imaging was performed in 33 patients with cerebral infarction treated in Zhumadian Central Hospital from Jan.2014 to Jan.2016.The cerebral blood flow (CBF),cerebral blood volume (CBV),peak time (TTP) and mean transit time (MTT) were measured in the infarct core area,ischemic penumbra (IP) and contralateral mirror area.The relative cerebral blood flow (rCBF),the relative cerebral blood volume (rCBV),relative peak time (rTTP),relative mean transit time (rMTT) in the infarct core area and IP were calculated and analyzed.Results Of the 33 patients,cranial scan found that 9 cases had the signs of early cerebral infarction,the remaining 24 cases found no abnormalities.33 patients underwent CTP imaging showed abnormal perfusion areas,of which 25 cases were found IP.Compared with the contralateral mirror area,CBV had no significant difference (P ＞0.05),and TTP,MTT were significantly prolonged,CBF decreased significantly,the difference was statistically significant (P ＜0.05).Compared with the infarction core area,the increase of CBF,CBV,TTP shortening and MTT prolongation were statistically significant (P＜0.05).There were significant differences on rCBF,rCBV,rTTP,rMTT between IP and infarct core area (P ＜ 0.05).IP was found in 10 patients with hyperacute cerebral infarction,11 cases of 15 patients with acute cerebral infarction and 4 cases of 11 patients in subacute phase.6 cases were in stage Ⅰ 2,12 cases in stage Ⅱ 1,7 cases in stage Ⅱ 2.Conclusion 320-detector row CT perfusion imaging can gain CT,CTP,CTA data by injection of contrast medium once,and provide clear imaging evidence for the area of cerebral lesions and the stage of IP in patients with cerebral infarction.It provides the possibility for clinical individualized treatment for patients,with a lower radiation dose and higher safety.关键词
脑梗死/320排动态容积CT/缺血半暗带(IP)/CT全脑灌注成像(CTP)Key words
Cerebral infarction/320-detector row CT/Ischemic penumbra (IP)/CT perfusion imaging分类
医药卫生
