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尼麦角林联合奥拉西坦治疗脑卒中后血管性认知功能障碍

毛彦明 李玉成

中国实用神经疾病杂志2017,Vol.20Issue(17):31-33,3.
中国实用神经疾病杂志2017,Vol.20Issue(17):31-33,3.DOI:10.3969/j.issn.1673-5110.2017.17.010

尼麦角林联合奥拉西坦治疗脑卒中后血管性认知功能障碍

Nicergoline combined oxiracetam in the treatment of vascular cognitive impairment after stroke

毛彦明 1李玉成2

作者信息

  • 1. 叶县人民医院神经内科,河南叶县467200
  • 2. 河南省人民医院,河南郑州450003
  • 折叠

摘要

Abstract

Objective To observe the clinical curative effect of nicergoline combined oxiracetam in the treatment of vascular cognitive impairment after stroke.Methods A total of 120 patients with cognitive impairment were randomly divided into nicergoline group and combination group,the nicergoline group was treated with nicergoline,the combination group was given nicergoline and oxiracetam combined treatment,the two groups were treated for 1 month.The cognitive function scores were cotnpared between the two groups by the Montreal cognitive assessment scale (MoCA) before and after the treatment,and clinical efficacy was compared between the two groups.Results The MoCA score of in the combined group was improved (5.97 ± 2.06),which was higher than (3.53±1.44) in the group,and the difference was statistically significant (t =4.21,P<0.01).The effective rate of combination group was better than that of the nicergoline group,the difference was statistically significant (P<0.05).Conclusion Nicergoline combined with oxiracetam has better effect compared to the single application of nicergoline,and can significantly improve the symptoms of vascular cognitive dysfunction after stroke and the quality of life.

关键词

脑卒中/血管性认知功能障碍/血管性痴呆/尼麦角林/奥拉西坦

Key words

Stroke/Vascular cognitive impairment/Nicergoline/Oxiracetam

分类

医药卫生

引用本文复制引用

毛彦明,李玉成..尼麦角林联合奥拉西坦治疗脑卒中后血管性认知功能障碍[J].中国实用神经疾病杂志,2017,20(17):31-33,3.

中国实用神经疾病杂志

1673-5110

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