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阿托伐他汀联合尤瑞克林治疗急性脑梗死临床观察

王建伟 尤书德

中国实用神经疾病杂志2017,Vol.20Issue(17):46-48,3.
中国实用神经疾病杂志2017,Vol.20Issue(17):46-48,3.DOI:10.3969/j.issn.1673-5110.2017.17.015

阿托伐他汀联合尤瑞克林治疗急性脑梗死临床观察

Clinical observation of atorvastatin and urinary kallidinogenase in the treatment of patients with acute cerebral infarction

王建伟 1尤书德2

作者信息

  • 1. 许昌县人民医院神经内科,河南许昌县461100
  • 2. 许昌市中心医院神经内2科,河南许昌461000
  • 折叠

摘要

Abstract

Objective To investigate the effect of atorvastatin and urinary kallidinogenase on eerebrovascular reserve (CVR) and nerve function in patients with acute cerebral infarction (ACI).Methods Ninety-four ACI patients treated in Department of Neurology,People's Hospital of Xuchang County were randomly divided into two groups,47 cases in each group.Two groups were given routine treatment;control group was also given atorvastatin,while observation group was given urinary kallidinogenase based on the control group.The CVR,nerve function,nitric oxide (NO) and level of blood pressure were compared between the two groups.Results The levels of CVR and NO in observation group were higher than those in control group,while the NIHSS was lower than control group (P<0.05).Before and after treatment,the levels of blood pressure in two groups had no obvious changes,there was no statistical difference (P>0.05).Conclusion Atorvastatin and urinary kallidinogenase in treatment of ACI can relax blood vessel,reduce plaque rupture,increase CVR,and decrease neurologic ischemia,which has application value.

关键词

急性脑梗死/阿托伐他汀/尤瑞克林/脑血管储备能力

Key words

Acute cerebral infarction/Atorvastatin/Urinary kallidinogenase/Cerebrovascular reserve

分类

医药卫生

引用本文复制引用

王建伟,尤书德..阿托伐他汀联合尤瑞克林治疗急性脑梗死临床观察[J].中国实用神经疾病杂志,2017,20(17):46-48,3.

中国实用神经疾病杂志

1673-5110

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