解放军医学杂志2017，Vol.42Issue(10)：854-859,6.DOI:10.11855/j.issn.0577-7402.2017.10.03
原发性纤毛不动综合征诊断方法的应用进展
Research progress of diagnostic approaches in primary ciliary dyskinesia
彭杨 1陈卓 2朱振潮 3张弛 2邱前辉2
作者信息
- 1. 510515 广州 南方医科大学研究生学院
- 2. 510080 广州 广东省人民医院,广东省医学科学院耳鼻咽喉头颈外科
- 3. 450052 郑州 郑州大学附属第一医院耳鼻咽喉头颈外科
- 折叠
摘要
Abstract
Primary ciliary dyskinesia (PCD) is an autosomal recessive or X-linked inherited disorder.The diagnosis of PCD is primarily based on clinical assessment accompanied with various supplementary methods,such as nasal nitric oxide (NO) examination,high-speed video microscopy,transmission electron microscopy and genetic tests.Some patients may fail to have a timely diagnosis resulted in delayed treatment since the devices and expertise limited in most medical centers.Recently,the use of immunofluorescence (IF) in PCD diagnosis is gaining acceptance within the clinical community.Specific antibodies against ciliary architecture are used in IF analyses to elucidate ciliary abnormality and are potentially important for early diagnosis of PCD.The present review summarizes the diagnostic methods of PCD with a focus on IF.关键词
原发性纤毛不动综合征/诊断/免疫荧光染色法Key words
primary ciliary dyskinesia/diagnosis/immunofluorescence分类
医药卫生引用本文复制引用
彭杨,陈卓,朱振潮,张弛,邱前辉..原发性纤毛不动综合征诊断方法的应用进展[J].解放军医学杂志,2017,42(10):854-859,6.
