林产化学与工业2017，Vol.37Issue(5)：68-78,11.DOI:10.3969/j.issn.0253-2417.2017.05.009
马鞭草烯酮基磺酸肟酯化合物的合成及抑菌活性
Synthesis and Antifungal Activity of Verbenone-based Oxime Sulfonate Compounds
摘要
Abstract
Verbenone was prepared by the selective oxidation of α-pinene at first.Then, twenty-two novel verbenone-based oxime sulfonate compounds(4a 4v)were synthesized by the oximation and O-sulfonylation reaction of the carbonyl group in verbenone . The target compounds were analyzed and characterized by FT-IR,1 H NMR,13 C NMR, and ESI-MS.Antifungal activity test showed that , at the mass concentration of 50 mg/L, the target compounds exhibited certain inhibition activity against the eight tested fungi.Inhibition rate of verbenone-based n-butyl oxime sulfonate(4u,R=(CH2)3CH3) against Rhizoctonia solani was 83.2%,inhibition rate of verbenone-based 2,4-difluorophenyl oxime sulfonate (4d,R=2,4-FPh) against Fusarium graminearum was 89.6%(better than the positive control chlorothalonil ),and inhibition rate of verbenone-based p-nitrophenyl oxime sulfonate (4n,R=p-NO2Ph)and 4u(R=(CH2)3CH3) against Cercospora arachidicola was 72.5%.关键词
α-蒎烯/马鞭草烯酮/磺酸肟酯/合成/抑菌活性Key words
α-pinene/verbenone/oxime sulfonate/synthesis/antifungal activity分类
化学化工引用本文复制引用
张瑞,段文贵,林桂汕,陈智聪,何冉,雷福厚..马鞭草烯酮基磺酸肟酯化合物的合成及抑菌活性[J].林产化学与工业,2017,37(5):68-78,11.基金项目
国家自然科学基金资助项目(31560194) （31560194）
广西林产化学与工程重点实验室开放基金资助项目( GXFC14-01) （ GXFC14-01）
广西大学"大学生创新创业训练计划"资助项目(201610593170) （201610593170）
