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活血化瘀法对子宫内膜异位症子宫内膜干细胞的影响

张继雯 宋殿荣 张葳 刘三洪 王玉华 杜文欣 郭洁 王雅楠

天津中医药2017,Vol.34Issue(11):756-759,4.
天津中医药2017,Vol.34Issue(11):756-759,4.DOI:10.11656/j.issn.1672-1519.2017.11.12

活血化瘀法对子宫内膜异位症子宫内膜干细胞的影响

Effets of promoting blood circulation and removing blood stasis for endometriosis-endometrial stem cells

张继雯 1宋殿荣 1张葳 1刘三洪 2王玉华 1杜文欣 1郭洁 1王雅楠1

作者信息

  • 1. 天津中医药大学第二附属医院妇科,天津 300150
  • 2. 天津中医药大学,天津 300193
  • 折叠

摘要

Abstract

[Objective] To investigate effect of promoting blood circulation and removing blood stasis on endometriosis endometrial stem cells. [Methods] Research of the treatment of endometriosis by the method of promoting blood circulation and removing blood stasis (Jianghuang San) to endometrial stem cells, which is include clone formation, mammosphere formationand endometrial-like tissue reconstitution in vivo. [Results] Jianghuang San coucld inhibit the proliferation of endometriosis-endometrial stem cellsobviously. There are statistical significance (P<0.05) between test group which added Jianghuang San and control group which added gestrinone to negative group which without any disposal in clone formation and mammosphere formation. The volume and the number of ectopic glands of tumor also have statistical significance (P<0.05) between high and middle group of Jianghuang San and control group to negative group. [Conclusion] Promoting blood circulation and removing blood stasis can prevent the proliferation of endometrial stem cells.

关键词

子宫内膜异位症/子宫内膜干细胞/活血化瘀法

Key words

endometriosis/endometrial stem cell/promoting blood circulation and removing blood stasis

分类

医药卫生

引用本文复制引用

张继雯,宋殿荣,张葳,刘三洪,王玉华,杜文欣,郭洁,王雅楠..活血化瘀法对子宫内膜异位症子宫内膜干细胞的影响[J].天津中医药,2017,34(11):756-759,4.

基金项目

中国博士后科学基金项目(201104309) (201104309)

国家自然科学基金项目(81303094). (81303094)

天津中医药

OACSTPCD

1672-1519

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