天然产物研究与开发2017，Vol.29Issue(10)：1654-1657,1694,5.DOI:10.16333/j.1001-6880.2017.10.004
花生衣提取液对离体血管环和心脏活动的影响
Effect of Peanut Skin Extract on Vascular Rings and Heart
摘要
Abstract
To study the effect of peanut skin extracts on vascular rings and heart.The perfusion model of thoracic aorta rings of rats and isolated frog heart were applied to observe the response of artery contraction of peanut skin extract and its active ingredient.High performance liquid chromatography (HPLC) was used to analyze and determine the active ingredient.The result showed that peanut skin extract can significantly relax the contraction of rat aortic ring induced by HCL and NE,and significantly reduce the heart rate and mean tension of frog isolated heart.The HPLC analysis results showed that resveratrol was one of the effective ingredients of peanut skin extract,which was consistent with the effect of peanut extract.In conclusion,peanut skin extract can significantly relax rat aortic ring,reduce the heart rate and mean tension of frog isolated heart.Peanut skin had the effect of vasorelaxation and heat protection.Its effective ingredient was resveratrol.关键词
花生衣/离体血管环/离体心脏/白藜芦醇Key words
peanut skin/isolated vascular rings/isolated/resveratrol分类
医药卫生引用本文复制引用
高良才,王欣怡,林泽杰,宋宁宁..花生衣提取液对离体血管环和心脏活动的影响[J].天然产物研究与开发,2017,29(10):1654-1657,1694,5.基金项目
上海市科委科研基金(16DZ2348900) （16DZ2348900）
国家大学生创新项目资助 （）
