天然产物研究与开发2017，Vol.29Issue(10)：1759-1765,7.DOI:10.16333/j.1001-6880.2017.10.021
不同炮制时间对何首乌成分及含量的影响
The Influence of Different Processing Time on Composition and Content of Polygoni Multiflori
摘要
Abstract
To study the content variation of chemical composition and best processing time for Polygoni Multiflori Radix.The content of Polygoni Multiflori Radix component with 6 different processing times were determined by HPLC and contrasted with market sale system.Fingerprint similarity analysis,cluster analysis and partial least squares regression analysis were adopted to analyze experimental data.The results demonstrated that the similarity was between 0.9 and 1.0,and there was a good correlation between the samples.Based on the composition of basic characteristics,six Polygoni Multiflori Radix samples were divided into 4 classifications by cluster analysis.PLS regression analysis showed that the content of stilbene glucoside and resveratrol had major differences at different processing times.4h was the best processing time.This study provided reference for quality control and further study of Polygoni Multiflori.关键词
何首乌/炮制时间/相似性分析/聚类分析/PLS回归分析Key words
Polygon multiflora/processing time/similarity analysis/cluster analysis/partial least squares analysis分类
医药卫生引用本文复制引用
周忆梦,赵梦杰,龚小红,党珏,袁岸,李燕,李芸霞..不同炮制时间对何首乌成分及含量的影响[J].天然产物研究与开发,2017,29(10):1759-1765,7.基金项目
中国科技部和澳门科学技术发展基金(007/2014/AMJ) （007/2014/AMJ）
开放基金的中药质量研究国家重点实验室(009) （009）
中国国家自然科学基金(81373943,81373583) （81373943,81373583）
四川青年科学技术基金会(2013JQ0018) （2013JQ0018）
四川省科技厅青年科技创新研究团队项目(2015TD0028,2016TD0006,2017TD0001 ) （2015TD0028,2016TD0006,2017TD0001 ）
