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反刍动物应激反应中糖皮质激素对免疫系统的调节机理

张千 李发弟 李飞

畜牧兽医学报2017,Vol.48Issue(5):785-792,8.
畜牧兽医学报2017,Vol.48Issue(5):785-792,8.DOI:10.11843/j.issn.0366-6964.2017.05.001

反刍动物应激反应中糖皮质激素对免疫系统的调节机理

Regulation Mechanism of Glucocorticoids to Immune System in Ruminants Stress Response

张千 1李发弟 1李飞2

作者信息

  • 1. 兰州大学草地农业科技学院,草地农业生态系统国家重点实验室,兰州730020
  • 2. 甘肃省肉羊繁育生物技术工程实验室,民勤733300
  • 折叠

摘要

Abstract

Glucocorticoids are effective and powerful anti-inflammatory substances,and make a wide inhibition on immune system.Glucocorticoids can regulate the immune system of the livestock by inhibiting the release of cytokines,inducing apoptosis,affecting immune cell differentiation and migration during the stress response,and inhibiting the immune system function of the livestock while reducing the inflammatory response,thereby which increase the risk of illness.In this article,the regulation mechanism of glucocorticoids to immune in ruminants stress response were discussed,focusing on glucocorticoid receptors expression,immune cells function and cytokines regulation,aiming to provide some references for related studies.

关键词

反刍动物/应激/免疫调节/糖皮质激素/细胞因子

Key words

ruminants/stress/immune regulation/glucocorticoids/cytokines

分类

农业科技

引用本文复制引用

张千,李发弟,李飞..反刍动物应激反应中糖皮质激素对免疫系统的调节机理[J].畜牧兽医学报,2017,48(5):785-792,8.

基金项目

甘肃省科技重大专项(1602NKDH020-03) (1602NKDH020-03)

公益性(农业)科研专项经费(201503134) (农业)

畜牧兽医学报

OA北大核心CSCDCSTPCD

0366-6964

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