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鸡脾转移因子对鸡肠道抗氧化能力的影响

胡君宜 李晶 卢嘉茵 王子旭 陈耀星 黄迪海 秦卓明 马保臣 董玉兰

畜牧兽医学报2017,Vol.48Issue(10):1990-1997,8.
畜牧兽医学报2017,Vol.48Issue(10):1990-1997,8.DOI:10.11843/j.issn.0366-6964.2017.10.023

鸡脾转移因子对鸡肠道抗氧化能力的影响

The Influence of Chicken Spleen Transfer Factor on Antioxidant Capacity of Chicken Intestine

胡君宜 1李晶 1卢嘉茵 1王子旭 1陈耀星 1黄迪海 2秦卓明 2马保臣 3董玉兰1

作者信息

  • 1. 中国农业大学动物医学院,北京100193
  • 2. 山东省农业科学院家禽研究所,济南250100
  • 3. 中国牧工商集团总公司,北京100070
  • 折叠

摘要

Abstract

The experiment was conducted to study the effect of chicken spleen transfer factor (TF)on intestine antioxidant capacity and the mechanism on production and immunity ability of chicken.One hundred chickens of 1-day-old were selected and were divided into 5 groups.Four TF groups including 20 chickens each received TF treatment as follows:0.05 mL (Minimum dose group),0.10 mL (Low dose group),0.25 mL (Medium dose group),1 mL (High dose group)per chicken TF were given for one week by drinking water every day from 5-days-old to 12-daysold,respectively,and then fed without TF to 19-days-old.Group 5th was normal control group.Fifty chickens were killed at 12-days-old and 19-days-old,respectively.The chickens were weighted,and the antioxidant capacity of the duodenum,jejunum,ileum and rectum were measured.The results showed that one week'treatment of TF showed an increased tendency of body weight,yet the effect was not obvious.However,the high TF dose group significantly increased the activity of SOD (17.07%-31.54%),CAT (16.98%-25.77%),GSH-PX (13.99%-23.59%)and T-AOC (16.48%-43.16%) of duodenum,jejunum,ileum and rectum,but significantly reduced the activity of MDA (P<0.05) in intestine.The activities of T-AOC,SOD in the intestinal segments,CAT (except for ileum) and GSH-PX (except for duodenum) were significantly increased in the middle dose groups (P<0.05),but the content of MDA was decreased significantly in the low and middle dose groups (P<0.05).At 19 days old,the changes of T-AOC,CAT,GSH-PX,SOD and MDA in each intestinal group were decreased compared with 12 days old,but there was still significant in individual intestinal segment (P<0.05).The results indicate that the TF,as a new feed additive,has a significant role in improving anti-oxidative stress ability.

关键词

转移因子//肠道/抗氧化

Key words

transfer factor/poultry/intestine/antioxidant

分类

农业科技

引用本文复制引用

胡君宜,李晶,卢嘉茵,王子旭,陈耀星,黄迪海,秦卓明,马保臣,董玉兰..鸡脾转移因子对鸡肠道抗氧化能力的影响[J].畜牧兽医学报,2017,48(10):1990-1997,8.

基金项目

国家自然科学基金(31372332 ()

31272483) ()

畜牧兽医学报

OA北大核心CSCDCSTPCD

0366-6964

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