中国实用外科杂志2017，Vol.37Issue(10)：1083-1088,6.DOI:10.19538/j.cjps.issn1005-2208.2017.10.04
从外科角度谈不可切除局部晚期胃癌整体治疗策略
Treatment strategy for unresectable local advanced gastric cancer from a surgical point of view
梁寒1
作者信息
- 1. 天津医科大学肿瘤医院胃部肿瘤科国家肿瘤临床医学研究中心天津市肿瘤防治重点实验室,天津300060
- 折叠
摘要
Abstract
According to Yoshida's stage Ⅳ gastric cancer classification,for some patients with marginally resectable and potentially unresectable metastatic gastric cancer,neoadjuvant intraperitoneal plus systematic chemotherapy (NIPS),cytoreductive surgery (CRS) plus hyperthermic intraperitoneal chemotherapy (HIPEC),palliative surgery plus chemotherapy,conversion therapy with docetaxel based three drug regimen and S1/paclitaxel chemotherapy plus apatinib may be benefited.For patients with moderate amount and more ascites,NIPS regimen may control the ascites,relieve symptoms and prolong the survival time.CRS + HIPEC has been demonstrated to provide survival benefit for patients with PCI (peritoneal cancer index) score ≤ 6.It is still controvertial whether the palliative surgery followed by chemotherapy may benefit for patient or not,but judicious use of surgical resection both gastrectomy and metastasis before chemotherapy in metastatic gastric cancer patients may result in favorable treatment approach.Conversion therapy with docetaxel based three drug regimen and chemotherapy combined with apatinib may result a high conversion rate.关键词
胃癌/不可切除/转化治疗/细胞减灭术/腹腔热灌注化疗Key words
gastric cancer/unresectable/conversion therapy/cytoreductive surgery (CRS)/hyperthermia intraperitoneal chemotherapy(HIPEC)分类
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梁寒..从外科角度谈不可切除局部晚期胃癌整体治疗策略[J].中国实用外科杂志,2017,37(10):1083-1088,6.
