中国实用外科杂志2017，Vol.37Issue(10)：1139-1142,4.DOI:10.19538/j.cjps.issn1005-2208.2017.10.18
晚期胃癌转化治疗后手术切除13例疗效分析
Eeffective analysis of conversion therapy for advanced gastric cancer: A report of 13 cases
甘强均 1张启 1李豪杰 1唐兆庆 1汪学非 1孙益红 1刘凤林1
作者信息
- 1. 复旦大学附属中山医院普外科,上海200032
- 折叠
摘要
Abstract
Objective To analyze the efficacy and safety of conversion therapy for advanced gastric cancer.Methods The clinical data of 13 cases of advanced gastric cancer underwent gastrectomy with D2 lymph node dissection after conversion therapy between January 2014 and July 2017 at Zhongshan Hospital,Fudan University were analyzed retrospectively.Results After conversion therapy,9 cases received PR,4 cases were SD.In all 13 cases,the number of lymph nodes resected was (47.5± 11.7);the surgical time was (1 80.9+38.2) min;the intraoperative blood loss was (203.9 + 92.3) mL;and no blood transfusion was performed during operation.The time of gastric tube indwelling was (52.0 + 30.8) h;the time of drainage tube placement was (170.2+47.0) h;the time to first liquid intake was (122.0+24.3) h;the time to first semifluid intake was (154.9+32.1) h;the postoperative hospital stay was (8.7+2.0) d.There were three cases of post-operative complications;one was intra-abdominal abscess and the rest two were pulmonary inflammation.According to Clavien Dindo classification for post-operative complications,only one was grade Ⅲ a and the rest got grade Ⅱ.There were no unplaned reoperation and death during hospitalization.The median PFS (progression-free survival) was 16.3 months;the median OS (overall survival) was 18.8 months.Conclusion Although conversion therapy increases the risk of postoperative complications slightly,some patients with advanced gastric cancer do get significant survival benefit;conversion therapy can be one of the important treatment methods for advanced gastric cancer.关键词
晚期胃癌/转化治疗/安全性/疗效Key words
advanced gastric cancer/conversion therapy/safety/efficacy分类
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甘强均,张启,李豪杰,唐兆庆,汪学非,孙益红,刘凤林..晚期胃癌转化治疗后手术切除13例疗效分析[J].中国实用外科杂志,2017,37(10):1139-1142,4.
